ArticleScientific reports2025
Potential links between serum uric acid levels and testosterone levels in adult males: a cross-sectional study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Simple virilizing form of 21-hydroxylase deficiency presenting with renal Insufficiency and polycythemia: a case report.Frontiers in endocrinology · 2026Article
- Uric Acid and Impulse Control Disorders in Parkinson's Disease: A Cross-Sectional Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Comparison of different insulin resistance surrogates in predicting hyperuricemia in non-diabetic Yi residents in Yunnan Province.Frontiers in endocrinology · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Given the controversial conclusion on the relationship between serum uric acid (SUA) levels and testosterone (T) levels in adult males, the purpose of this study is to explore the association between SUA levels and T levels in adult males. We conducted a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2011 to 2016. The association was estimated using multiple linear regression model and results are presented as β with its 95% confidence intervals (95% CIs). This study enrolled 7791 males aged 18 years or older and found a negative correlation between serum uric acid levels and testosterone levels after controlling for confounding factors. Additionally, a non-linear association was observed, with an infection point of 4.4 mg/dL for serum uric acid levels. The effect sizes on the left and right sides of the inflection point were determined as 17.93 (- 3.61 to 39.48) and - 14.73 (- 18.51 to - 10.95), respectively. Elevated SUA levels were found to be linked to decreased T levels, even after controlling for confounders. Moreover, non-linear pattern in the relationship between SUA levels and T levels was also identified.
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Registered trials
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