Evidence map›Paper›PMID 40374783›Full record

ArticleAesthetic plastic surgery2025

Skin-and Nipple-Sparing Mastectomy with Immediate Breast Reconstruction via Prepectoral Prosthesis Placement Approach and Lipofilling of the Skin Cover for Small- and Medium-Sized Breasts: A Retrospective Study.

Walid M Abd El Maksoud, Yasser S Ahmed, Alaa Hamza, Maha A Alghamdi, Mohamed Alhashash, Pakinam A Rizk, Fahad S Al Amri, Khaled S Abbas, Abdullah Dalboh, Hassan A Alzahrani and 6 more

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Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Walid M Abd El MaksoudDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia. wabdulmksoud@kku.edu.sa.ORCID 0000-0002-2861-6611
Yasser S AhmedExperimental Surgery Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID 0000-0002-5198-2417
Alaa HamzaExperimental Surgery Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID 0009-0006-6690-5621
Maha A AlghamdiDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0003-1306-9616
Mohamed AlhashashExperimental Surgery Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID 0000-0001-8555-4413
Pakinam A RizkMedical Research Institute, Alexandria University, Alexandria, Egypt.ORCID 0009-0008-3289-7437
Fahad S Al AmriDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0001-6706-7646
Khaled S AbbasDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0002-0447-9915
Abdullah DalbohDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0002-8964-0455
Hassan A AlzahraniDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0003-0712-1959
Marei H AlshandeerDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0001-9764-3333
Khadija M BawahabCollege of Medicine, King Khalid University, Abha, Saudi Arabia.ORCID 0009-0006-1106-2321
Sally Mohamed HegabMedical Research Institute, Alexandria University, Alexandria, Egypt.ORCID 0009-0004-1032-9827
Nour A AbdelmohsenDepartment of General Surgery, Alexandria University Hospital, Alexandria, Egypt.
Ahmad Jebril M BosailyDepartment of General Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Mohamed H SultanExperimental Surgery Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID 0000-0002-7481-5179

Funding

Deanship of Scientific Research, King Khalid University RGP2/535/46
6 · The paper itself

Abstract

backgroundsWe aimed to assess the feasibility and outcomes of immediate breast reconstruction with prepectoral direct prosthesis placement under the skin envelope in patients with small-to medium-sized breasts with immediate lipofilling of the skin cover.

methodsDemographic and clinical data of female patients with small-to medium-sized breasts diagnosed with breast cancer who were eligible for skin-sparing mastectomy and immediate reconstruction were included in this retrospective study. Information concerning the surgical technique, implant size, procedure duration, and intraoperative complications were also obtained. All early or late postoperative complications were recorded. Postoperative patient satisfaction was routinely assessed using the Kyungpook National University Hospital Breast Reconstruction Satisfaction Questionnaire.

resultsThe study included data from 52 female patients (mean age: 49.1±8.6years); the mean follow-up was 30.3 ± 9.7 months. Reconstruction was successful in 50 (96.2%) patients. Capsule contracture developed in 11 patients (21.2%), with six requiring capsulectomy. Three patients (5.8%) showed a slight reduction in the range of motion, mainly due to axillary procedures. Two patients (3.8%) developed rippling that was treated successfully with delayed lipofilling. Forty-eight patients (92.3%) showed postoperative satisfaction, with three being satisfied only after the management of postoperative complications.

conclusionsThe prepectoral technique for breast reconstruction without mesh support is an effective option in patients with small-to medium-sized breasts. This approach has few complications and offers high postoperative patient satisfaction at a reasonable cost. Proper patient selection is necessary to achieve favorable outcomes, and immediate lipofilling improves the results. Moreover, immediate lipofilling seems to improve outcomes of prepectoral breast reconstruction; however, future studies are required to support this finding. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Breast ImplantationBreast NeoplasmsMammaplastyMastectomy, SubcutaneousAdipose TissueAdultBreast ImplantsCohort StudiesEstheticsFeasibility StudiesFemaleFollow-Up StudiesHumansMastectomyMiddle AgedNipplesBreast cancerBreast reconstructionLipofillingOncoplastic surgeryPrepectoral implant approachSmall- and medium-sized breasts

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.