Evidence map›Paper›PMID 40374675›Full record

ArticleScientific reports2025

End-to-end Chinese clinical event extraction based on large language model.

Bo An, Haitao Zhang, Longlong Ma, Zhen Zhao

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bo An *Laboratory for Ethnic Minority Languages, Cultures and Behaviors, Institute of Ethnology and Anthropology, Chinese Academy of Social Sciences, Haidian, Beijing, 100081, China.
Haitao Zhang *Department of Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, Jimo, Shanghai, 200120, China. zht11322@easthospital.cn.
Longlong MaInstitute of Software, Chinese Academy of Sciences, Haidian, Beijing, 100190, China.
Zhen ZhaoDepartment of Emergency, Beijing Friendship Hospital, Capital Medical University, Xicheng, Beijing, 100050, China.

Funding

Database Funding of the Chinese Academy of Social Sciences 2024SJK017National Natural Science Foundation of China 62266036National Social Science Foundation of China 22BTQ010
6 · The paper itself

Abstract

Clinical event extraction is crucial for structuring medical data, supporting clinical decision-making, and enabling other intelligent healthcare services. Traditional approaches for clinical event extraction often use pipeline-based methods to identify event triggers and elements. However, these methods commonly suffer from error propagation and information loss, leading to suboptimal performance. To address this challenge, this paper proposes an end-to-end clinical event extraction method based on the large language models (LLMs). Specifically, we transform the clinical event extraction task into an end-to-end text generation task and design a prompt learning method based on the LLMs called LMCEE. Experimental results demonstrate a significant improvement over traditional pipeline methods, with the F1 score increasing by 12%. Additionally, the proposed method outperforms the generative-based method named UIE, showcasing a 5.7% improvement in F1 score. However, the experimental results also disclose certain limitations of the proposed method, such as its sensitivity to prompt templates and its heavy dependence on the type of LLMs. These findings highlight the need for further investigation and optimization to enhance performance and robustness.

Indexed as

Data MiningNatural Language ProcessingAlgorithmsChinaClinical Decision-MakingHumansLarge Language ModelsClinical event extractionLarge language modelPrompt learning

Identifiers

PMID40374675
PMCPMC12081896

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.