ArticleScientific reports2025
Clinical outcomes following endometrial receptivity assessment-guided personalized euploid embryo transfer in patients with previous implantation failures.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Endometrial receptivity-guided embryo transfer: a systematic review and meta-analysis of the evidence.Journal of assisted reproduction and genetics · 2026Pooled it
- Optimizing the Endometrial Factor in Recurrent Implantation Failure: From Established Diagnostics to Mechanism-Informed Management.Journal of clinical medicine · 2026Review
- Advances in multi-omics and aging clock research for female reproductive health and aging.MedScience · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate potential improvements when implementing endometrial receptivity analysis (ERA)-guided personalized embryo transfer (pET) using euploid blastocyst in patients with one or more previous failed embryo transfers. A total of 270 patients with one or more previous failed embryo transfers were enrolled between 2017 and 2021 in this multicenter retrospective study. These patients were divided into two groups: study cases (ERA-guided pET) (n = 200) or controls (standard embryo transfer) (n = 70). Clinical outcomes compared were pregnancy rate (PR), implantation rate (IR), ongoing pregnancy rate (OPR), and live birth rate (LBR). Clinical results in terms of PR, OPR, and LBR were significantly higher when performing ERA-guided pET (PR: 65.0%; OPR: 49.0%; LBR: 48.2%) compared to standard embryo transfer (PR: 37.1%; OPR: 27.1%; LBR: 26.1%) (P < 0.01). Logistic regression was applied to examine the correlation between ERA and the primary outcome measured, OPR, including demographic variables as covariates. The effect of ERA was significantly associated with OPR (P = 0.002; aOR 2.8, 95% CI 1.5-5.5); furthermore, OPR decreased significantly when body mass index (BMI) values increased (P = 0.04; aOR 0.9, 95% CI 0.8-0.98). These findings support the potential of ERA-guided pET to improve clinical outcomes and address the challenges encountered by patients with previous implantation failures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.