Evidence map›Paper›PMID 40374637›Full record

ArticleNature communications2025

Chemotactic Zn micromotor for treatment of high blood ammonia-associated hepatic encephalopathy.

Ye Feng, Chao Gao, Xiuyun Peng, Bin Chen, Miaomiao Ding, Dailing Du, Jinghui Rong, Qi Lv, Daniela A Wilson, Yingfeng Tu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Artificial chemotaxis in micro/nanomotors.Nature communications · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ye FengSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Chao GaoSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Xiuyun PengKey Laboratory of Joint Diagnosis and Treatment of Chronic Liver Disease and Liver Cancer of Lishui, Lishui People's Hospital, Lishui, China.
Bin ChenSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Miaomiao DingSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Dailing DuSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Jinghui RongSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Qi LvSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Daniela A WilsonInstitute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-8796-2274
Yingfeng TuGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.ORCID http://orcid.org/0000-0003-2605-0172
Fei PengSchool of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, China. pengf26@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0001-8817-3472

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22175083
6 · The paper itself

Abstract

Hepatic fibrosis involves hepatocyte damage, causing blood ammonia accumulation, which exacerbates liver pathology and crosses the blood-brain barrier, inducing hepatic encephalopathy. It is meaningful to construct a therapeutic platform for targeted ammonia clearance. In this work, a biocompatible water-powered Zn micromotor is constructed as an ammonia chemotaxis platform, which can be actuated by the water splitting reaction and the self-generated Zn

Indexed as

AmmoniaChemotaxisHepatic EncephalopathyZincAnimalsHepatocytesHumansHyperammonemiaLiverLiver CirrhosisMaleMiceAmmoniaZinc

Identifiers

PMID40374637
PMCPMC12081644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.