Evidence map›Paper›PMID 40374524›Full record

ArticleWorld journal of surgery2025

Sarcopenia With High Subcutaneous Fat Predicts Metabolic Dysfunction Associated Steatotic Liver Disease Development After Pylorus Preserving Pancreaticoduodenectomy.

Masashi Nakagawa, Naokazu Chiba, Shigeto Ochiai, Takahiro Gunji, Toru Sano, Koichi Tomita, Masatoshi Shigoka, Satoshi Tabuchi, Eiji Hidaka, Shigeyuki Kawachi

Abstract read
In one paragraph

Article in World journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Masashi NakagawaDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.ORCID 0009-0009-5046-0105
Naokazu ChibaDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Shigeto OchiaiDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Takahiro GunjiDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Toru SanoDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Koichi TomitaDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Masatoshi ShigokaDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Satoshi TabuchiDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Eiji HidakaDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.
Shigeyuki KawachiDepartment of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMASLD after PPPD affects not only the long-term prognosis but also the availability of postoperative adjuvant chemotherapy, its prevention and treatment are important issues. The aim of this study is to analyze whether objective preoperative factors could predict the development of postoperative MASLD in patients after PPPD.

methodsA total of 171 patients who underwent PPPD at our institute between April 2012 and May 2022 were retrospectively enrolled. We evaluated several CT findings, including various body fat areas and psoas muscles. The variables, including the CT findings and histopathological findings, were compared between the patients with and without MASLD after PPPD.

resultsMASLD after PPPD developed 40 patients (23.4%). The clinical factors identified as predictive of postoperative MASLD on univariate analysis were sex (p < 0.001), subcutaneous fat area (p = 0.006), and psoas muscle area at the L3 level (p < 0.001) by univariate analysis. The multivariate analysis revealed subcutaneous fat area (odds ratio [OR] = 3.694, 95% confidence interval [CI]:1.315-10.377, p = 0.013) and psoas muscle area of the L3 level (OR = 0.223, 95%CI: 0.079-0.633, p = 0.005) as independent predictive factors for postoperative NAFLD.

conclusionHigh subcutaneous fat accumulation and reduced psoas muscle area (sarcopenia) were identified as independent risk factors for the development of MASLD after PPPD.

Indexed as

Fatty LiverPancreaticoduodenectomyPostoperative ComplicationsSarcopeniaSubcutaneous FatAgedFemaleHumansMaleMiddle AgedOrgan Sparing TreatmentsPsoas MusclesRetrospective StudiesRisk FactorsTomography, X-Ray ComputedMASLDPPPDsarcopeniasubcutaneous fat

Identifiers

PMID40374524
PMCPMC12134198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.