Evidence map›Paper›PMID 40373878›Full record

ReviewAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2025

Unraveling CD8

Joel S Freibaum, Riley P Leathem, William Braaton, Scott M Krummey

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joel S FreibaumDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Riley P LeathemDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
William BraatonDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Scott M KrummeyDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. Electronic address: skrumme1@jhmi.edu.

Funding

Role of the CD43 Receptor on Effector CD8+ T Cells During Acute Allograft RejectionR56AI179856 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KRUMMEY, SCOTT M · 2024 to 2024
$328k
NIAID NIH HHS R56 AI179856
6 · The paper itself

Abstract

Early experimental investigations of alloimmunity demonstrated that the T cell response against allogeneic antigens is robust and results from a high precursor frequency of responding clones. Seminal studies using cell culture-based methods led to an overall model in which CD8

Indexed as

CD8-Positive T-LymphocytesIsoantigensAnimalsHumansMiceIsoantigensalloimmunityantigen recognitionCD8+ T cellpeptide-MHC complextolerance

Identifiers

PMID40373878
PMCPMC12599394

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.