Evidence map›Paper›PMID 40373763›Full record

ArticleNeuro-degenerative diseases2025

Characteristics of Neuromuscular Ultrasound in Patients with Amyotrophic Lateral Sclerosis.

Jieying Wu, Hongsong Song, Mukadas Arkin, Shuo Zhang, Xiao Huang, Dongsheng Fan, Yingsheng Xu

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Article in Neuro-degenerative diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jieying WuDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Hongsong SongDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Mukadas ArkinDepartment of Neurology, Beijing Puhua International Hospital, Beijing, China.
Shuo ZhangDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Xiao HuangDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Dongsheng FanDepartment of Neurology, Peking University Third Hospital, Beijing, China, dsfan2010@aliyun.com.
Yingsheng XuDepartment of Neurology, Peking University Third Hospital, Beijing, China, xys@bjmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeuromuscular ultrasound has been increasingly used in the detection and diagnosis of amyotrophic lateral sclerosis (ALS), commonly characterized by peripheral nerve atrophy, degeneration, and muscle fasciculations. The aim of this study was to assess the ultrasound characteristics of ALS patients.

methodsA total of 67 consecutive patients with sporadic ALS and 19 with ALS mimics (63.16% peripheral neuropathy) were recruited. Ultrasound and electrophysiological examinations were performed; the peripheral nerve cross-sectional area (CSA) and fasciculation grades were compared between the groups, and correlations between ultrasound and electrophysiological data in ALS patients were determined.

resultsALS patients had smaller proximal median and ulnar nerve CSAs than those of ALS mimics, who exhibited asymmetric changes. Fasciculation differences in the trapezius, triceps brachii, extensor digitorum communis, thenar, and first dorsal interosseous muscles were observed. In ALS patients, the CSA and fasciculation relative scores were correlated with electrophysiological indicators.

conclusionUltrasound is a valuable tool for monitoring peripheral nerve CSA and muscle fasciculations, both of which correlate with electrophysiological indices, in ALS patients.

Indexed as

Amyotrophic Lateral SclerosisMuscle, SkeletalAdultAgedElectromyographyFasciculationFemaleHumansMaleMiddle AgedUltrasonographyAmyotrophic lateral sclerosisCross-sectional areaElectrophysiologyFasciculationsNeuromuscular ultrasound

Identifiers

PMID40373763
PMCPMC12688379

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