Evidence map›Paper›PMID 40373106›Full record

ArticlePloS one2025

Association between lipid accumulation product and endometriosis: A cross-sectional study from NHANES 1999-2006.

Jing Zhe, Yanxing Cai, Yakun Bi

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jing ZheCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Guiyang Maternal and Child Health Care Hospital, Guiyang Children's Hospital, Guiyang, China.
Yanxing CaiDepartment of Clinical Laboratory, Guiyang Maternal and Child Health Care Hospital, Guiyang Children's Hospital, Guiyang, China.
Yakun BiScience and Technology Management Center, Guiyang Maternal and Child Health Care Hospital, Guiyang Children's Hospital, Guiyang, China.ORCID https://orcid.org/0009-0001-8766-9158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association of lipid accumulation product (LAP) and the likelihood of endometriosis prevalence has not been previously mentioned. The research aimed to assess the possible potential association between LAP and endometriosis in nationwide research. This cross-sectional analysis was conducted on 2,216 participants selected from the National Health and Nutrition Examination Survey (NHANES) in the 1999-2006 cycles. Logistic regression and stratified analysis by age, race, level of education, BMI, marital status, PIR, glycohemoglobin, drinking, and smoking status were used to analyze the association of the LAP index and odds of endometriosis prevalence. Moreover, smoothed curve fitting was used to evaluate the relevancy of LAP and endometriosis. The multivariate logistic regression model showed a positive association between ln LAP and endometriosis. This trend remained after a full adjustment (odds ratio = 1.37, 95% confidence interval:1.08-1.75, P = 0.010). Compared to the minimum ln LAP quartile, participants in the highest ln LAP had a 93% higher chance of endometriosis incidence (odds ratio = 1.93, 95% confidence interval: 1.08-3.46, P = 0.027). After conducting subgroup analysis and interaction testing, it was found that this positive association was most prominent among women aged 35 years and above and participants with glycohemoglobin≥6%. This nationwide study suggested that an elevated ln LAP was related to an increased endometriosis prevalence. Therefore, LAP may be a valuable tool for predicting the occurrence of endometriosis. Follow-up studies are critical to assess the association between LAP and odds of endometriosis prevalence and explain the potential mechanisms of this relationship.

Indexed as

EndometriosisLipid Accumulation ProductAdultCross-Sectional StudiesFemaleHumansMiddle AgedNutrition SurveysPrevalenceRisk FactorsYoung Adult

Identifiers

PMID40373106
PMCPMC12080788

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.