Evidence map›Paper›PMID 40373033›Full record

SynthesisJMIR mental health2025

Evaluating Generative AI in Mental Health: Systematic Review of Capabilities and Limitations.

Liying Wang, Tanmay Bhanushali, Zhuoran Huang, Jingyi Yang, Sukriti Badami, Lisa Hightow-Weidman

Abstract readSystematic Review
In one paragraph

Synthesis in JMIR mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Strengths and Potential Pitfalls of the Use of Artificial Intelligence in Psychiatric Education and Practice.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liying WangInstitute on Digital Health and Innovation, College of Nursing, Florida State University, 222 S Copeland St, Tallahassee, FL, 32306, United States, 1 (850) 644-3296.ORCID 0000-0002-3123-2328
Tanmay BhanushaliCollege of Arts and Sciences, University of Washington, Seattle, WA, United States.ORCID 0009-0008-2838-5084
Zhuoran HuangKhoury College of Computer Sciences, Northeastern University, Boston, MA, United States.ORCID 0000-0002-0270-6096
Jingyi YangTeachers College, Columbia University, New York, NY, United States.ORCID 0009-0008-1570-4111
Sukriti BadamiCollege of Arts and Sciences, University of Washington, Seattle, WA, United States.ORCID 0009-0002-0778-1287
Lisa Hightow-WeidmanInstitute on Digital Health and Innovation, College of Nursing, Florida State University, 222 S Copeland St, Tallahassee, FL, 32306, United States, 1 (850) 644-3296.ORCID 0000-0002-2421-923X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The global shortage of mental health professionals, exacerbated by increasing mental health needs post COVID-19, has stimulated growing interest in leveraging large language models to address these challenges. objectives: This systematic review aims to evaluate the current capabilities of generative artificial intelligence (GenAI) models in the context of mental health applications. Methods: A comprehensive search across 5 databases yielded 1046 references, of which 8 studies met the inclusion criteria. The included studies were original research with experimental designs (eg, Turing tests, sociocognitive tasks, trials, or qualitative methods); a focus on GenAI models; and explicit measurement of sociocognitive abilities (eg, empathy and emotional awareness), mental health outcomes, and user experience (eg, perceived trust and empathy). Results: The studies, published between 2023 and 2024, primarily evaluated models such as ChatGPT-3.5 and 4.0, Bard, and Claude in tasks such as psychoeducation, diagnosis, emotional awareness, and clinical interventions. Most studies used zero-shot prompting and human evaluators to assess the AI responses, using standardized rating scales or qualitative analysis. However, these methods were often insufficient to fully capture the complexity of GenAI capabilities. The reliance on single-shot prompting techniques, limited comparisons, and task-based assessments isolated from a context may oversimplify GenAI's abilities and overlook the nuances of human-artificial intelligence interaction, especially in clinical applications that require contextual reasoning and cultural sensitivity. The findings suggest that while GenAI models demonstrate strengths in psychoeducation and emotional awareness, their diagnostic accuracy, cultural competence, and ability to engage users emotionally remain limited. Users frequently reported concerns about trustworthiness, accuracy, and the lack of emotional engagement. Conclusions: Future research could use more sophisticated evaluation methods, such as few-shot and chain-of-thought prompting to fully uncover GenAI's potential. Longitudinal studies and broader comparisons with human benchmarks are needed to explore the effects of GenAI-integrated mental health care.

Indexed as

Artificial IntelligenceCOVID-19Mental DisordersMental HealthHumansclinical skillsdigital mental health interventionevaluationgenerative artificial intelligencelarge language modelLLMmental health

Identifiers

PMID40373033
PMCPMC12097452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.