Evidence map›Paper›PMID 40372779›Full record

ArticleeLife2025

Sensorimotor delays constrain robust locomotion in a 3D kinematic model of fly walking.

Lili Karashchuk, Jing Shuang Li, Grant M Chou, Sarah Walling-Bell, Steven L Brunton, John C Tuthill, Bingni W Brunton

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Inhibitory circuits control leg movements duringbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Lili Karashchuk *Neuroscience Graduate Program, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0001-6244-8239
Jing Shuang Li *Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, United States.ORCID https://orcid.org/0000-0003-4931-8709
Grant M ChouDepartment of Neurobiology and Biophysics, University of Washington, Seattle, United States.
Sarah Walling-BellDepartment of Neurobiology and Biophysics, University of Washington, Seattle, United States.
Steven L BruntonDepartment of Mechanical Engineering, University of Washington, Seattle, United States.
John C Tuthill *Department of Neurobiology and Biophysics, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0002-5689-5806
Bingni W Brunton *Department of Biology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0002-4831-3466

Funding

Project 4: Neural Basis of Behavioral SequencesU19NS104655 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI WILSON, RACHEL · 2017 to 2021
$14.6M
Neural coding of leg proprioceptionR01NS102333 · NINDS · UNIVERSITY OF WASHINGTON · PI John Tuthill · 2017 to 2026
$3.6M
Air Force Office of Scientific Research FA9550-19-1-0386Alfred P. Sloan Foundation Sloan Research FellowshipNational Science Foundation Graduate Research Fellowship ProgramNatural Sciences and Engineering Research Council of Canada PGSD3-557385-2021NIH HHS R01NS102333NINDS NIH HHS R01 NS102333NINDS NIH HHS U19 NS104655
6 · The paper itself

Abstract

Walking animals must maintain stability in the presence of external perturbations, despite significant temporal delays in neural signaling and muscle actuation. Here, we develop a 3D kinematic model with a layered control architecture to investigate how sensorimotor delays constrain the robustness of walking behavior in the fruit fly,

Indexed as

DrosophilaDrosophila melanogasterLocomotionWalkingAnimalsBiomechanical PhenomenaModels, Biologicalcomputational biologyD. melanogastergenerative modellocomotor controlneurosciencequantifying behaviorsensorimotor delaysystems biologywalking

Identifiers

PMID40372779
PMCPMC12081000

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.