Evidence map›Paper›PMID 40372670›Full record

ArticleMolecular neurobiology2025

Metabolomic Profiling in Ischemic Stroke: Unraveling the Influence of Obesity and Identifying Potential Biomarkers Using

Fuyan Liu, Xinlei Song, Haolin Zhang, Yuqiu Li, Xiao-Feng Zhang

Abstract read
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In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fuyan Liu *School of Biological Sciences and Technology, University of Jinan, Jinan, 250022, China.
Xinlei Song *Qilu Hospital, Shandong University, Jinan, 250012, China.
Haolin ZhangSchool of Public Health, Tianjin Medical University, Tianjin, 300070, China.
Yuqiu LiQilu Hospital, Shandong University, Jinan, 250012, China. liyuqiu@sdutcm.edu.cn.
Xiao-Feng ZhangSchool of Biological Sciences and Technology, University of Jinan, Jinan, 250022, China. bio_zhangxf@ujn.edu.cn.

Funding

the start-up project of University of Jinan No. XBS 160100362the talent start-up project of University of Jinan No.1009509University Research Project of Shandong Province J18KA274
6 · The paper itself

Abstract

Ischemic stroke (IS) is emerging as an increasingly serious social issue with elusive etiology, few diagnostic markers, and limited treatment methods. Another concern in contemporary society is the prevalence of obesity, which is indicative of suboptimal well-being. Despite its association with established risk factors for stroke (such as hypertension and diabetes), several studies have reported a controversial phenomenon known as the "obesity paradox," whereby certain obese patients with stroke exhibited unexpectedly positive outcomes. In this study, a total of 68 plasma samples were collected including 36 controls and 32 IS patients, with further differentiation between obese and non-obese individuals in each group. A quantitative metabonomic approach based on

Indexed as

BiomarkersIschemic StrokeMetabolomeMetabolomicsObesityProton Magnetic Resonance SpectroscopyAgedFemaleHumansMaleMiddle AgedBiomarkersIschemic stroke (IS)MetabolomicNMR spectroscopyObesityPotential biomarkers

Identifiers

PMID40372670

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.