Evidence map›Paper›PMID 40372540›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2025

Borrelidin M: a new borrelidin derivative obtained from Streptomyces rochei VL-16 exhibited potent antibacterial and antiproliferative properties.

Vinoth Vengadesan, Jagan Muniyandi, Neha Yadav, Premkumar G, Ajit Ramesh Sawant, Lakshmi Sankaranarayanan, Prashanth K, Toka Swu, Sudha Rani Sadras

Abstract read
PubMed Publisher
In one paragraph

Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vinoth VengadesanDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, India.
Jagan MuniyandiDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, India.
Neha YadavDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, India.
Premkumar GDepartment of Chemistry, Pondicherry University, Puducherry, India.
Ajit Ramesh SawantDepartment of Biotechnology, Pondicherry University, Puducherry, India.
Lakshmi SankaranarayananDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, India.
Prashanth KDepartment of Biotechnology, Pondicherry University, Puducherry, India.
Toka SwuDepartment of Chemistry, Pondicherry University, Puducherry, India.
Sudha Rani SadrasDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, India. sadrassudha@pondiuni.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lookout for novel metabolites to overcome the threat imposed by antibiotic resistant pathogens is on the rise globally. The present study reports on the identification and characterisation of a new borrelidin derivative from Streptomyces rochei VL-16 strain that was isolated from the soil samples of Osudu Lake in Puducherry. The active compound produced by Streptomyces rochei VL-16 strain was purified sequentially by thin layer, column and high performance liquid chromatography techniques. The purified compound was subsequently identified as borrelidin through Q-TOF-HR-LCMS, FTIR and UV-Vis spectroscopy techniques. Based on integration proton NMR signals and HR-ESI-MS peak pattern, the compound was further identified as a new derivative of borrelidin. Its 3D structure was optimised using density functional theory. The new derivative obtained in this study was designated as borrelidin M (C

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsFatty AlcoholsStreptomycesBacteriaCell Line, TumorCell ProliferationHumansMicrobial Sensitivity TestsSoil MicrobiologyAnti-Bacterial AgentsAntineoplastic AgentsborrelidinFatty AlcoholsActinobacteriaAntibacterialAntiproliferativeBorrelidinFT-IRHR-ESI–MS

Identifiers

PMID40372540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.