Evidence map›Paper›PMID 40372520›Full record

ArticleFood and environmental virology2025

Presence of Potentially Infectious Human Enteric Viruses and Antibiotic Resistance Genes in Mussels from the Campania Region, Italy: Implications for Consumer's Safety.

Iolanda Venuti, Enric Cuevas-Ferrando, Irene Falcó, Inés Girón-Guzmán, Marina Ceruso, Tiziana Pepe, Gloria Sánchez

Abstract read
In one paragraph

Article in Food and environmental virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Detection of an ExPEC-likeBiotech (Basel (Switzerland)) · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iolanda VenutiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino, N. 1, 80137, Naples, Italy.
Enric Cuevas-FerrandoInstitute of Agrochemistry and Food Technology, IATA-CSIC, Av. Agustín Escardino 7, 46980, Paterna, Valencia, Spain. enriccuefe@gmail.com.
Irene FalcóInstitute of Agrochemistry and Food Technology, IATA-CSIC, Av. Agustín Escardino 7, 46980, Paterna, Valencia, Spain.
Inés Girón-GuzmánInstitute of Agrochemistry and Food Technology, IATA-CSIC, Av. Agustín Escardino 7, 46980, Paterna, Valencia, Spain. ines.giron@iata.csic.es.
Marina CerusoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino, N. 1, 80137, Naples, Italy.
Tiziana PepeDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino, N. 1, 80137, Naples, Italy.
Gloria SánchezInstitute of Agrochemistry and Food Technology, IATA-CSIC, Av. Agustín Escardino 7, 46980, Paterna, Valencia, Spain.

Funding

European Union MS21-006Generalitat Valenciana ACIF/2021/181Generalitat Valenciana CIAPOT/2022/20
6 · The paper itself

Abstract

This study presents a comprehensive assessment of viral contamination and antibiotic resistance genes (ARGs) presence in mussels (Mytilus galloprovincialis) (n = 60) collected from retail stores in the Campania region (Italy). High prevalence of human noroviruses (HuNoV) genogroup I (GI) (77%) and genogroup II (GII) (40%), rotaviruses (RV) (60%), and astroviruses (HAstV) (25%) was found, with average levels of 4.34, 5.09, 5.05, and 4.00 Log genome copies (GC)/g, respectively. All samples tested negative for hepatitis A and E viruses. Viral faecal contamination indicators, including somatic coliphages (88%, 3.62 mean Log plaque forming units (PFU)/100 g) and crAssphage (50%, 3.72 mean Log GC/g), showed strong correlations (ρ > 0.65, p-value < 0.05) with HuNoV GII, HAstV, and RV concentrations in mussels. The study also investigated the presence of respiratory viruses, with all samples testing negative for SARS-CoV-2, respiratory syncytial virus, and influenza A virus.Furthermore, a capsid-integrity RT-qPCR assay was applied to selected positive samples, confirming the presence of potentially infectious viruses and underscoring the associated risks to consumers.Additionally, ARGs were detected by qPCR, targeting beta-lactams, quinolones, and chloramphenicol resistance genes in both the total and the bacteriophage fractions of selected samples.Overall, this study emphasizes the importance of continued surveillance and strategic interventions to mitigate public health risks associated with the consumption of contaminated bivalve molluscan shellfish (BMS), which may imply the dissemination of infectious enteric viruses and ARGs within communities.

Indexed as

BivalviaDrug Resistance, MicrobialEnterovirusMytilusShellfishAnimalsAnti-Bacterial AgentsConsumer Product SafetyFood ContaminationHumansItalyNorovirusRotavirusAnti-Bacterial AgentsARGsFoodborne virusesFood safetyViability RT-qPCR

Identifiers

PMID40372520
PMCPMC12081582

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.