Evidence map›Paper›PMID 40372508›Full record

ArticleActa neurochirurgica2025

Intraosseous ultrasound for assessment of pedicle screw holes in the thoracolumbar spine based on endoscopic ultrasound: An experimental study.

Yun Dong, XiongXiong Zuo, HaiTao Sun, He Wang, ShaoHui He, JianRu Xiao, XiaoPan Cai

Abstract read
In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yun DongDepartment of Biomedical Engineering, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.ORCID 0000-0003-2040-6799
XiongXiong ZuoDepartment of Medical Imaging, Shanghai East Hospital, Shanghai, China.
HaiTao SunDepartment of Orthopedics Oncology, Changzheng Hospital, Naval Medical University, Shanghai, China.
He WangDepartment of Ultrasonic Medicine, Shanghai East Hospital, Shanghai, China.
ShaoHui HeDepartment of Orthopedics Oncology, Changzheng Hospital, Naval Medical University, Shanghai, China.
JianRu XiaoDepartment of Orthopedics Oncology, Changzheng Hospital, Naval Medical University, Shanghai, China. jianruxiao83@163.com.
XiaoPan CaiDepartment of Orthopedics Oncology, Changzheng Hospital, Naval Medical University, Shanghai, China. caipan1982@163.com.ORCID 0000-0002-0104-4238

Funding

Multi-center clinical study on standardized comprehensive diagnosis and treatment of pathological fractures,China 23Y31900200National Natural Science Foundation of China 81871470The project of orthopedic clinical medical research center construction approved by The Science and Technology Commission of Shanghai Municipality,China 21MC1930100Top priority research center construction project approved by Shanghai Municipal Health Commission,China 2022ZZ01013
6 · The paper itself

Abstract

purposeExperimental assessment of the efficiency of intraosseous ultrasound (IOUS) utilizing the mini probe of endoscopic ultrasound (EUS) is performed to determine the accuracy of pedicle screw hole placements in thoracolumbar spine.

methodsDrill holes in 76 pedicles of thoracolumbar spines from 2 cases of goats. Each pedicle screw hole is subjected to a 360° circumferential IOUS scanning with a catheter-type mini ultrasound probe of EUS and to a CT examination. Subsequently, all ultrasound images were independently interpreted by 3 reviewers without knowledge of the real position of screw holes and the results of the CT examination for the assessment of screw hole malposition and pedicle cortex breach. Finally, according to the conclusion of CT, a Chi-square test is employed to assess the differences of interpretations of the screw hole malposition among the all reviewers and the relevant relationship between the recognition of the misplaced screw holes and imaging methods utilized.

resultsCT revealed 13 correctly positioned holes and 63 holes deviating from correct position (including holes that penetrated the cortex). All ultrasound images with malposition identified by CT were correctly interpreted, with no false negatives and no intra-reviewer differences. There were no omissions of severe malposition (including the spinal canal was penetrated into). Excluding six false positives misjudged due to the intersection of screw holes on both sides, there was also no discrepancy between the EUS and CT imaging in the interpretation of screw hole malposition. The examination time of each pedicle screw hole with EUS took less than 15 s.

conclusionEUS-based IOUS is an immediate, reliable and lower-cost technique for accurate determination of pedicle screw hole malposition. With a probe that is both flexible and not easily bendable, the EUS is particularly suitable for IOUS, especially in the narrow space of the bone gaps or bone canals, and minimally invasive spine surgery (MISS).

Indexed as

EndosonographyLumbar VertebraePedicle ScrewsThoracic VertebraeAnimalsGoatsTomography, X-Ray ComputedEndoscopic ultrasoundIntraosseous ultrasoundMalpositionPedicle screw holeThoracolumbar spine

Identifiers

PMID40372508
PMCPMC12081567

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.