Evidence map›Paper›PMID 40372488›Full record

ArticlePflugers Archiv : European journal of physiology2025

Thermosensitivity of TREK K2P channels is controlled by a PKA switch and depends on the microtubular network.

Sönke Cordeiro, Marianne Musinszki

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sönke CordeiroInstitute of Physiology, Kiel University, Kiel, Germany. s.cordeiro@physiologie.uni-kiel.de.ORCID 0000-0002-1049-8303
Marianne MusinszkiInstitute of Physiology, Kiel University, Kiel, Germany.ORCID 0000-0002-5597-6735

Funding

Deutsche Forschungsgemeinschaft FOR2518
6 · The paper itself

Abstract

Temperature sensing is an essential component of animal perception and enables individuals to avoid painful or lethal temperatures. Many temperature sensors in central and peripheral neurons are ion channels. Here, we focus on the thermosensitive TREK/TRAAK subfamily of K2P channels-the only known K

Indexed as

Cyclic AMP-Dependent Protein KinasesMicrotubulesPotassium Channels, Tandem Pore DomainThermosensingAnimalsHEK293 CellsHumansPhosphorylationTemperatureCyclic AMP-Dependent Protein Kinasespotassium channel protein TREK-1Potassium Channels, Tandem Pore DomainIon channelK2P channelMicrotubule networkTemperature sensingThermosensitivityTREK

Identifiers

PMID40372488
PMCPMC12152049

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.