Evidence map›Paper›PMID 40372454›Full record

SynthesisArchives of orthopaedic and trauma surgery2025

The impact of surgical approach in total hip arthroplasty on the organisms profile of periprosthetic joint infections? A systematic review and meta-analysis.

Ashraf T Hantouly, Sathish Muthu, Jad Lawand, Osama Alzobi, Mohanad Alebbini, Amir Human Hoveidaei, Mehdi Karimi, Shamsi Hameed, Ghalib Ahmed, Mustafa Citak

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07436065 (Postoperative Orthopedic Wound Dressing Using Sterile Versus Clean Non-sterile Techniques At Hamad General Hospital. A Prospective Pilot Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07436065 nacompletednot on this map

Postoperative Orthopedic Wound Dressing Using Sterile Versus Clean Non-sterile Techniques At Hamad General Hospital. A Prospective Pilot Study

TypeinterventionalSponsorHamad Medical CorporationRan2021 to 2024Enrolled25ConditionsSurgical Site Infection (SSI)ArmsSterile Glove Dressing Technique, Clean Non-Sterile Glove Dressing Technique
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashraf T HantoulyAspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar.
Sathish MuthuDepartment of Orthopaedics, Government Medical College, Karur, TN, 639004, India.
Jad LawandUniversity of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555-0569, USA.
Osama AlzobiDepartment of Orthopaedic Surgery, Surgical Specialty Center, Hamad Medical Corporation, Doha, Qatar.
Mohanad AlebbiniDepartment of Orthopaedic Surgery, Surgical Specialty Center, Hamad Medical Corporation, Doha, Qatar.
Amir Human HoveidaeiInternational Center for Limb Lengthening, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, MD, USA.
Mehdi KarimiBogomolets National Medical University (NMU), Kyiv, Ukraine.
Shamsi HameedDepartment of Orthopaedic Surgery, Surgical Specialty Center, Hamad Medical Corporation, Doha, Qatar.
Ghalib AhmedDepartment of Orthopaedic Surgery, Surgical Specialty Center, Hamad Medical Corporation, Doha, Qatar.
Mustafa CitakDepartment of Orthopaedic Surgery, HELIOS ENDO-Clinic Hamburg, Holstenstraße, 222767, Hamburg, Germany. mcitak@gmx.de.ORCID http://orcid.org/0000-0003-3207-7101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the impact of the surgical approach in total hip arthroplasty (THA) on the organism profile associated with periprosthetic joint infections (PJI).

methodsThis systematic review and meta-analysis rigorously followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Four online databases (Medline, Embase, Web of Science, Scopus) were searched from inception till the 2nd of Sep 2023. The focus was all articles reporting the organism profile of hip periprosthetic joint infections in relation to the utilized surgical approach. Exclusion criteria encompassed studies lacking infecting organism specification by surgical approach, technical studies, review articles, case reports, non-English articles and inaccessible full-text articles. Quality assessment was done utilizing the Methodological Index for Non-Randomized Studies (MINORS) criteria.

resultsA total of 529 microorganism profiles associated with 285 PJIs were analyzed from 11 studies including 44,271 THA patients. The overall rate of PJI in THA noted in the included studies is 0.64%. No significant difference between the direct anterior approach (DAA) and THA other approaches was noted in the incidence of PJI (OR 1.06, 95% CI [0.67, 1.67], p = 0.92). Similarly, no significant difference between the DAA and other THA approaches was noted in the incidence of gram-negative pathogen induced PJI (OR 3.35, 95% CI [0.49, 22.88], p = 0.22).

conclusionThe overall rate of PJI in THA remain low. Utilization of DAA does not increase the risk of PJI compared to other approaches. Further, DAA does not increase the incidence of gram-negative pathogen induced PJI in THA. However, the available evidence on the organism profile based on the surgical approach is limited, and further studies are needed to make robust conclusions.

Indexed as

Arthroplasty, Replacement, HipProsthesis-Related InfectionsHip ProsthesisHumansPeriprosthetic joint infectionSurgical approachTotal hip arthroplasty

Identifiers

PMID40372454

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.