Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors.
Dong-Jae JunDepartment of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.
Marc M SchumacherDepartment of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.ORCID 0000-0002-5527-4215
Youngah JoDepartment of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.
Rebecca A FaulknerDepartment of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.ORCID 0000-0003-1619-0497
Yangyang YangDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.
Jet TsienDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.
Tian QinDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.ORCID 0000-0001-7225-3224
Russell A DeBose-BoydDepartment of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.ORCID 0000-0002-7452-5227
Funding
Tissue Culture & Antibody Production CoreP01HL160487 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI Helen Haskell Hobbs · 2022 to 2026
$14.9M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeff G McDonald · 2022 to 2026
$7.4M
Development of Sulfur-Based Reactions with Translational ApplicationsR01GM141088 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Tian Qin · 2021 to 2026
$2.1M
Significance of UBIAD1 in Regulation of HMG CoA Reductase Degradation, Mevalonate Metabolism, and Menaquinone-4 SynthesisR01GM144039 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI BOOTH, SARAH LOUISE, DEBOSE-BOYD, RUSSELL ALFRED · 2021 to 2024
Schnyder corneal dystrophy (SCD) is a rare autosomal dominant condition characterized by the opacification of the cornea owing to the abnormal deposition of cholesterol. SCD-associated mutations have been identified in the gene encoding UbiA prenyltransferase domain-containing protein-1 (UBIAD1), which uses geranylgeranyl pyrophosphate (GGpp) to synthesize the vitamin K
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Allosteric regulation of UBIAD1 trafficking from ER to Golgi revealed by chemical genetic screening. · full record | OpenQuestion