Evidence map›Paper›PMID 40372326›Full record

ReviewJACC. Clinical electrophysiology2025

Hexagonal Multielectrode Design for Recording Local Electrograms With Superior Characteristics.

Mark G Hoogendijk, Ruben Coronel, Rishi Arora, Marion Kuiper, Natasja de Groot, Rudolf A de Boer, Edward J Vigmond, Bastiaan J Boukens

Abstract readReview
In one paragraph

Review in JACC. Clinical electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mark G HoogendijkDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, the Netherlands. Electronic address: m.hoogendijk@erasmusmc.nl.
Ruben CoronelHeart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Center, Amsterdam, the Netherlands.
Rishi AroraDepartment of Cardiology, University of Chicago, Chicago, Illinois, USA.
Marion KuiperDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
Natasja de GrootDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, the Netherlands.
Rudolf A de BoerDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, the Netherlands.
Edward J VigmondIHU Institut LIRYC, Fondation University Bordeaux, Talence, France; Institute of Mathematics of Bordeaux, UMR 5251, University of Bordeaux, Talence, France.
Bastiaan J BoukensDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands; Laboratory of Experimental Cardiology, Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, the Netherlands.

Funding

New and Disruptive Therapeutic Approaches to Target Fundamental Molecular Mechanisms Underlying Atrial FibrillationR35HL161249 · NHLBI · UNIVERSITY OF CHICAGO · PI Rishi Arora · 2022 to 2026
$5.1M
The identification and pathophysiology of non-infarcted but injured myocardium in the post-ischemic heartR01HL152712 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI, ZHAO, MING · 2021 to 2024
$3.0M
NHLBI NIH HHS R01 HL152712NHLBI NIH HHS R35 HL161249
6 · The paper itself

Abstract

Electrograms recorded with a local coaxial reference offer advantages over bipolar electrograms for activation mapping but require more electrodes. We demonstrate that these coaxial electrograms can be recorded with a triangular local reference that can be efficiently created using hexagonal multielectrode grids. Triangular and cross-shaped local references recorded with a custom multielectrode were virtually indistinguishable. In contrast to bipolar electrograms, the morphology of the coaxial electrograms was insensitive to electrode orientation relative to the activation front, and the activation time matched closely with local activation. Developing hexagonal multielectrode designs may improve the efficiency and precision of clinical activation mapping.

Indexed as

ElectrocardiographyElectrophysiologic Techniques, CardiacElectrodesEquipment DesignHumansactivation mappingcatheterelectrogrammultielectrode

Identifiers

PMID40372326
PMCPMC12915988

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.