Evidence map›Paper›PMID 40372076›Full record

ArticleAmerican journal of hypertension2025

A Comparative Study of the Clinical Efficacy of Superselective Adrenal Artery Embolization for Patients with Primary Aldosteronism.

L Wang, R Xiang, J Chang, M Mao, R Feng, L Tao, P Tang, Y P Zhao, Z Zuo, D S Gao and 10 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in American journal of hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Primary aldosteronism: pharmacotherapyFrontiers in endocrinology · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

L WangDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0009-0002-7735-1901
R XiangDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
J ChangDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
M MaoDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
R FengDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
L TaoDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
P TangDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Y P ZhaoDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Z ZuoDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
D S GaoDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
P PuDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
W HuangDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
X LiDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
J ChenDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
H ZhaoDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Q Y ShiDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
F J LvDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Y T HeDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
N A KhanDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Z X XuDepartment of Cardiovascular Medicine, Cadiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-3294-268X

Funding

2024 Nursing Subject Advancement Plan-Key Project of the School ofNational Natural Science Foundation 82101651Nursing's "Seed Plan" 20240302
6 · The paper itself

Abstract

backgroundSuperselective adrenal artery embolization (SAAE) is a potential treatment option for patients with primary aldosteronism (PA).

methodsThis retrospective study aimed to compare the clinical efficacy and impact on cardiorenal organs of SAAE with mineralocorticoid receptor antagonists (MRA) and adrenalectomy (ADX) in patients with PA. After a median follow-up of 19 (12.5-26.5) months, 148 patients with PA were included in the study. The study cohorts consisted of 58, 53, and 37 patients treated with SAAE, MRA, and ADX, respectively.

resultsDuring follow-up, SAAE achieved a significantly greater level of complete clinical success in the treatment of PA compared to MRA (P < 0.05). Within the SAAE group (n = 58), 19 (32.8%) and 26 (44.8%) patients achieved complete and partial clinical success, respectively. However, there were no significant differences in the prognostic parameters of the cardiorenal organs between the two groups. In the comparison of patients with UPA treated with SAAE (n = 35) and ADX (n = 37), there was no significant difference in clinical efficacy between the two groups.

conclusionsThe findings of this study suggest that for patients with PA who are not suitable for ADX, SAAE is a viable treatment option that significantly improves clinical outcomes compared to MRA treatment.

Indexed as

Adrenal GlandsEmbolization, TherapeuticHyperaldosteronismAdrenalectomyAdultAgedFemaleHumansMaleMiddle AgedMineralocorticoid Receptor AntagonistsRetrospective StudiesTreatment OutcomeMineralocorticoid Receptor Antagonistsbilateral adrenal hyperplasiablood pressurechocolatehypertensionprimary aldosteronismsuperselective adrenal artery embolization

Identifiers

PMID40372076

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.