SynthesisOrthopaedic surgery2025
The Perioperative Resource Use and Effectiveness of Patellofemoral Arthroplasty Versus Total Knee Arthroplasty: A Meta-Analysis.
Synthesis in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patellofemoral vs. total knee arthroplasty for isolated patellofemoral osteoarthritis: evidence-based recommendations from a systematic review with GRADE assessment.Archives of orthopaedic and trauma surgery · 2026Pooled it
- Patellofemoral Joint Replacement for Isolated Patellofemoral Osteoarthritis: Mid- to Long-Term Survivorship and Functional Outcomes.Journal of personalized medicine · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectivePatellofemoral osteoarthritis (PFOA) is a common condition that significantly affects quality of life. With advancements in modern patellofemoral arthroplasty (PFA) prostheses, a growing number of surgeons are opting for PFA to treat isolated PFOA. This meta-analysis aimed to compare the perioperative resource use and therapeutic outcomes of PFA versus total knee arthroplasty (TKA) in patients with isolated PFOA.
methodsA literature search was conducted in PubMed, EMBASE, the Cochrane Library, and the Web of Science until November 2024. The included studies provided direct comparisons of perioperative resource use (surgical time, blood loss, and length of stay) and postoperative outcomes (patient-reported outcome measures [PROMs], quality of life, and patient satisfaction) between modern PFA and TKA in patients with isolated PFOA. The Cochrane risk of bias assessment tool was applied to randomized controlled trials, and the modified Newcastle-Ottawa Scale was used for observational studies to evaluate methodological quality and risk of bias. Data was extracted from eligible studies and combined to calculate the mean difference (MD) or pooled relative risk with a 95% confidence interval (CI).
resultsWe included eight eligible studies with a mean follow-up duration of 2-10 years. Compared with TKA, modern PFA demonstrated significantly shorter surgical times (MD = -13.67 min; 95% CI: -20.47 to -6.86) and reduced perioperative blood loss. However, no significant difference was observed in hospital length of stay. Regarding PROMs, PFA showed superior functional outcomes on the Oxford Knee Score (OKS) within 2 years postoperatively (MD = -2.02; 95% CI: -3.77 to -0.26). No significant differences were found between PFA and TKA at 12-month follow-up for the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) function score (MD = -5.68; 95% CI: -21.54 to 10.18) or total WOMAC score (MD = -6.65; 95% CI: -30.00 to 16.70). Similarly, at 24-month follow-up, no differences were observed in the University of California, Los Angeles activity score (MD = -0.02; 95% CI: -1.79 to 1.75) or final OKS (MD = -1.09; 95% CI: -6.31 to 4.14). Quality of life and patient satisfaction remained comparable between the two procedures throughout the first 2 years and final follow-up.
conclusionsPFA demonstrates comparable efficacy to TKA in isolated PFOA, with superior early functional recovery within the first 2 years post-surgery, shorter surgical duration, and reduced blood loss. These findings suggest PFA may be a resource-efficient alternative for eligible patients.
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