Evidence map›Paper›PMID 40371936›Full record

SynthesisNursing open2025

Effectiveness of Nurse-Led Early Mobility Protocols on the Outcomes of Critical Care Patients: A Systematic Review and Meta-Analysis.

Jing Xu, Shengyuan Wang, Qian Zhang, Yanfen Yao, Jing Yu

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nursing open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Effectiveness of Nurse-led Interventions on Pain and Complications among Patients Admitted to Intensive Care Unit: A Quasi-experimental study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing XuDepartment of Intensive Care Unit, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.ORCID https://orcid.org/0009-0000-4727-7224
Shengyuan WangDepartment of Rehabilitation Medicine, Shandong Mental Health Center, Jinan, Shandong, China.
Qian ZhangDepartment of Intensive Care Unit, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Yanfen YaoDepartment of Intensive Care Unit, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Jing YuDepartment of Intensive Care Unit, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis review evaluates the effectiveness of nurse-led early mobility protocols on key patient outcomes, including length of ICU and hospital stay, body function, mobility, muscle strength and mortality.

designSystematic review and meta-analysis.

methodsThis review was conducted, following PRISMA 2020 guidelines. Outcomes assessed included ICU stay, hospital stay, body function, mobility, muscle strength, and mortality. Meta-analysis using a random-effects model calculated pooled estimates such as weighted mean differences (WMD) and standardised mean differences (SMD) for continuous outcomes, and risk ratios (RR) for mortality.

resultsThe pooled WMD indicated that nurse-led early mobility protocols significantly reduced ICU stay by 1.8 days (WMD: -1.813; 95% CI: -3.072 to -0.555) and hospital stay by 2.6 days (WMD: -2.622; 95% CI: -5.122 to -0.123). No significant effects were observed for mobility (SMD: -0.245), body function (SMD: 0.223), muscle strength (SMD: 0.385) or mortality (RR: 1.117). Heterogeneity was substantial for most outcomes. Nurse-led early mobility protocols effectively reduce ICU and hospital stay durations, suggesting their role in optimising critical care recovery. However, further high-quality studies are needed to determine their impacts on other functional outcomes and long-term recovery. No patient or public contribution.

Indexed as

Critical CareEarly AmbulationHumansIntensive Care UnitsLength of StayMuscle Strengthcritical careintensive care unitmeta‐analysisnurse

Identifiers

PMID40371936
PMCPMC12079643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.