Evidence map›Paper›PMID 40371710›Full record

ArticleeLife2025

Single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts reveals transcriptional complexity in the insect central complex.

Derek G Epiney, Gonzalo Morales Chaya, Noah R Dillon, Sen-Lin Lai, Chris Q Doe

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Regulatory logic of neuronal differentiation in theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Modern Mining: The Role of Single-cell RNA Sequencing in Advancing Neuroscience Research.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Regulatory logic of neuronal identity specification inbioRxiv : the preprint server for biology · 2025
    Article
  8. Cell cycle-dependent cues regulate temporal patterning of thebioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Cell type-specific driver lines targeting thebioRxiv : the preprint server for biology · 2025
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Derek G Epiney *Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.
Gonzalo Morales Chaya *Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.
Noah R Dillon *Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.
Sen-Lin LaiInstitute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.ORCID https://orcid.org/0000-0002-7531-283X
Chris Q DoeInstitute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.ORCID https://orcid.org/0000-0001-5980-8029

Funding

DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007348 · NICHD · UNIVERSITY OF OREGON · PI Chris Q Doe, KRYN STANKUNAS · 1989 to 2026
$6.8M
GENETIC AND MOLECULAR STUDIES OF NEUROGENESISR01HD027056 · NICHD · UNIVERSITY OF OREGON · PI Chris Q Doe · 1989 to 2026
$5.0M
Genetic and Molecular Studies of NeurogenesisR37HD027056 · NICHD · UNIVERSITY OF OREGON · PI DOE, CHRIS Q · 2012 to 2021
$3.0M
Graduate Training Grant in GeneticsT32GM149387 · NIGMS · UNIVERSITY OF OREGON · PI Karen J Guillemin · 2023 to 2026
$1.6M
NICHD NIH HHS R01 HD027056NICHD NIH HHS R37 HD027056NICHD NIH HHS T32 HD007348NIGMS NIH HHS T32 GM149387NIH HHS 5-T32-GM149387NIH HHS 5-T32-HD07348NIH HHS HD27056
6 · The paper itself

Abstract

In both

Indexed as

BrainDrosophila melanogasterNeural Stem CellsNeuronsTranscription, GeneticAnimalsFemaleMaleNeurogliaSequence Analysis, RNASingle-Cell Analysiscentral complexdevelopmental biologyD. melanogasterneuroblastneuropeptidessingle cell RNA sequencingtranscription factorstype II neuroblast

Identifiers

PMID40371710
PMCPMC12081001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.