ArticleJournal of the American Heart Association2025
Nomogram for Predicting 1-, 3-, and 5-Year Survival in Hemodynamically Significant Aortic Regurgitation: The ARISE Score.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
backgroundA user-friendly tool that integrates key clinical variables to estimate prognosis in aortic regurgitation is lacking. We aimed to develop and validate a nomogram-based score to predict survival and identify high-risk patients for timely aortic valve surgery referral. METHODS AND
resultsFrom 2008 to 2022, 1229 patients (derivation data set: 764 Taiwanese; validation data set: 465 Japanese; age: 64±17 years) with isolated chronic moderately severe to severe aortic regurgitation from 3 centers were included. All echocardiograms were reviewed de novo. At a median follow-up of 5.0 (interquartile range, 2.2-8.2) years, 204 all-cause deaths occurred and 247 underwent aortic valve surgery within 3 months. In multivariable analysis, age (
conclusionsThe ARISE score (https://arise-score.vercel.app/), which includes guideline-recommended parameters, effectively predicts survival in patients with aortic regurgitation. It may facilitate shared decision-making between the heart team and patients.
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