Evidence map›Paper›PMID 40371597›Full record

ArticleJournal of the American Heart Association2025

Anatomical and Functional Predictors of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation.

Susanne Jung, Markus Kondruweit, Mohamed Marwan, Stephan Achenbach

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07343674 (PERFECT - Portuguese Evolut Registry Studying the Outcomes of Medtronic Evolut™ FX+ TAVI System by Evaluating an Optimal Care Pathway for TAVI), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07343674 recruitingnot on this mapstarted 2026, after this paper: background citation

PERFECT - Portuguese Evolut Registry Studying the Outcomes of Medtronic Evolut™ FX+ TAVI System by Evaluating an Optimal Care Pathway for TAVI

Typeobservational_patient_registrySponsorPortuguese Association of Interventional CardiologyRan2026 to 2028Enrolled500ConditionsSevere Symptomatic Aortic Stenosis (Defined as New York Heart Association (NYHA) Class ≥ II)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susanne JungDepartment of Cardiology Friedrich-Alexander-Universität Erlangen-Nürnberg, University Hospital Erlangen Erlangen Germany.ORCID 0000-0002-4031-6304
Markus KondruweitDepartment of Cardiac Surgery Friedrich-Alexander-Universität Erlangen-Nürnberg, University Hospital Erlangen Erlangen Germany.
Mohamed MarwanDepartment of Cardiology Friedrich-Alexander-Universität Erlangen-Nürnberg, University Hospital Erlangen Erlangen Germany.ORCID 0000-0001-8759-4101
Stephan AchenbachDepartment of Cardiology Friedrich-Alexander-Universität Erlangen-Nürnberg, University Hospital Erlangen Erlangen Germany.ORCID 0000-0002-7596-095X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-degree atrioventricular block with the need for permanent pacemaker (PPM) implantation represents a frequent complication after transcatheter aortic valve implantation (TAVI). Extension of indication for TAVI toward subjects with lower surgical risk requires reduction of the likelihood for the need for PPM implantation. The aim of the current analysis was to identify predictors of the need for PPM implantation after TAVI. METHODS AND

resultsIn a cohort of 1500 consecutive patients without a PPM undergoing transfemoral TAVI, clinical and procedural characteristics as well as parameters derived from cardiac computed tomography, such as membranous septal length and calcium volumes of the aortic valve cusps and the left ventricular outflow tract were assessed. Median calcium volume of the aortic valve was 552 mm

conclusionsThe current analysis offers a detailed examination of predictors for the need for PPM implantation after TAVI. Our results may contribute to improved risk stratification on the need for PPM implantation after TAVI.

Indexed as

Aortic ValveAortic Valve StenosisAtrioventricular BlockCalcinosisCardiac Pacing, ArtificialPacemaker, ArtificialTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesRisk AssessmentRisk FactorsTomography, X-Ray Computedatrioventricular blockcardiac computed tomographypermanent pacemakertranscatheter aortic valve implantation

Identifiers

PMID40371597
PMCPMC12184600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.