ArticleInfection and drug resistance2025
Prevalence, Risk Factors, and Clinical Outcomes with Advanced HIV Disease Among People with Newly Diagnosed HIV During the "Treat-All" Era: A Retrospective Cohort Study From Xi'an City, China.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Article
- Late HIV Diagnosis and Associated Factors Among Newly Reported HIV/AIDS Cases AgedChina CDC weekly · 2026Article
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8 authors.
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Abstract
Purpose: China launched "treat-all" in 2016 to make all HIV-positive people eligible for ART regardless of disease stage. Widespread treatment may not eliminate advanced HIV. This study investigated the prevalence, characteristics, risk factors, and clinical outcomes of advanced HIV disease (AHD) in newly diagnosed HIV-positive individuals in China during the "treat-all" period. Patients and methods: We performed a retrospective cohort study on newly diagnosed adult ART-naive people with HIV (PWH) in Xi'an from 2016 to 2022. The prevalence of AHD and six-month mortality/loss to follow-up (LTFU) were investigated. Risk variables for AHD and predictors of mortality or LTFU in the cohort were investigated using multivariate logistic and Cox regression, respectively. Results: Of the PWH, 47.5% (2999/6318) had AHD at HIV diagnosis. At enrollment, being ≥50 years (aOR: 1.75, 95% CI: 1.44-2.12, Conclusion: Under the "treat-all" policy, Xi'an had a high prevalence of AHD upon HIV diagnosis. AHD predicted 6-month mortality. Urgent implementation of targeted strategies is necessary to minimize AHD.
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