Evidence map›Paper›PMID 40371383›Full record

ArticleJournal of neurology & neuromedicine2019

The Human Leukocyte Antigen (HLA) DRB1*13:02 Allele Protects against Dementia in Continental Western Europe.

Lisa M James, Apostolos P Georgopoulos

Abstract read
In one paragraph

Article in Journal of neurology & neuromedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Brain communications · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
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  10. Article
  11. Immunogenetic clustering of 30 cancers.Scientific reports · 2022
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lisa M JamesBrain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis, MN, 55417, USA.
Apostolos P GeorgopoulosBrain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis, MN, 55417, USA.

Funding

Intramural VA VA999999
6 · The paper itself

Abstract

Human Leukocyte Antigen (HLA) Class II DRB1*13 alleles have recently been found to protect against age-related brain deterioration, even in the presence of apolipoprotein E4 (apoE4),

Indexed as

Apolipoprotein EDementiaHuman Leukocyte AntigenPersistent Antigens

Identifiers

PMID40371383
PMCPMC12077165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.