Evidence map›Paper›PMID 40371306›Full record

ArticleSAGE open medical case reports2025

Refractory pediatric actinic prurigo successfully treated with upadacitinib: A case report.

Florence Morissette, Jérome Coulombe

Abstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Isolated Actinic Prurigo Cheilitis in an Elderly Thai Female: An Atypical Presentation.Clinical, cosmetic and investigational dermatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Florence MorissetteDermatology Division, Department of Medicine, CHUM, University of Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-9535-2353
Jérome CoulombeDermatology Division, Department of Pediatrics, CHU Sainte-Justine, Montreal, QC, Canada.ORCID https://orcid.org/0000-0003-1261-3093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actinic prurigo is a rare photodermatosis, usually occurring during childhood. Pruritic papulonodules on sun-exposed areas are frequently associated with cheilitis and conjunctivitis. The most widely accepted pathophysiology to date is a type IV hypersensitivity reaction triggered by ultraviolet radiation. This case report describes a 12-year-old boy suffering from refractory actinic prurigo, who was successfully treated with the janus kinase inhibitor upadacitinib.

Indexed as

pediatricsphotodermatitistreatments

Identifiers

PMID40371306
PMCPMC12075963

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.