Evidence map›Paper›PMID 40371233›Full record

ArticleGastro hep advances2025

Discrepancy in Metabolic Dysfunction-Associated Steatotic Liver Disease Prevalence in a Large Northern California Cohort.

Luis A Rodriguez, Lue-Yen S Tucker, Varun Saxena, Theodore R Levin

Abstract read
In one paragraph

Article in Gastro hep advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis A RodriguezDivision of Research, Kaiser Permanente Northern California, Pleasanton, California.
Lue-Yen S TuckerDivision of Research, Kaiser Permanente Northern California, Pleasanton, California.
Varun SaxenaDivision of Research, Kaiser Permanente Northern California, Pleasanton, California.
Theodore R LevinDivision of Research, Kaiser Permanente Northern California, Pleasanton, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: The estimated prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in US adults is 31.3%. However, little is known about MASLD diagnosis rates in clinical practice. We used data from electronic health records and assessed the annual MASLD prevalence. Methods: We conducted a repeated cross-sectional analysis of a retrospective dynamic cohort study among 2,040,688-2,852,060 Kaiser Permanente Northern California adult members without other chronic liver diseases from 2009 to 2018. Annual MASLD prevalence was identified based on International Classification of Diseases, Ninth or Tenth Revision, Clinical Modification diagnosis codes, the application of natural language processing of all radiology imaging report text that included the liver, and the application of the Dallas Steatosis Index, a MASLD prediction algorithm. Results: Between 2009 and 2018, the estimated MASLD prevalence ranged from 0.37% to 0.95% using diagnosis codes, 0.88%-1.37% using imaging, and 6.14%-11.27% using the Dallas Steatosis Index. Conclusion: Reliance on diagnosis codes or natural language processing on hepatic imaging, or the Dallas Steatosis Index, to identify MASLD patients within a large health-care system yields much lower than expected prevalence. These results underscore an underdiagnosis issue and highlight the need for improved diagnostic practices.

Indexed as

AdultsDallas Steatosis IndexDiagnosis CodesImagingMASLD Prevalence

Identifiers

PMID40371233
PMCPMC12076719

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.