SynthesisFrontiers in neurology2025
Acupuncture for chronic insomnia disorder: a systematic review with meta-analysis and trial sequential analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of different intervention modalities combined with exercise in patients with insomnia: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- Sleep and endocrine effects of acupuncture for insomnia: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2026Pooled it
- Effectiveness and Safety of Electroacupuncture in Patients with Treatment-Resistant Insomnia: A Randomized, Assessor-Blinded, Waitlist-Controlled Pilot Trial.Nature and science of sleep · 2026Trial
- Brain functional changes in chronic partial sleep-deprivation population by electroacupuncture at shenmen(HT7) and neiguan (PC6) acupoints: A BOLD-fMRI study.Integrative medicine research · 2026Article
- Acupuncture on 5-hydroxytryptamine levels and clinical outcomes in depression: A systematic review and meta-analysis of randomized controlled trials.World journal of psychiatry · 2026Article
- Acupuncture-related peripheral stimulation as a candidate neuromodulatory model of insomnia: clinical evidence, sleep-wake circuitry, and translational limits.Frontiers in neuroscience · 2026Review
- Wearable low-level laser therapy (laser acupuncture) versus manual acupuncture for chronic insomnia: protocol for a randomized, assessor-blinded, superiority trial.Frontiers in psychiatry · 2026Article
- Ultrasound-guided stellate ganglion acupuncture for chronic insomnia disorder using fNIRS: study protocol for a randomized controlled trial.Frontiers in neurologyArticle
- Electroacupuncture modulates electroencephalographic microstate dynamics to alleviate chronic insomnia: a machine learning approach for predicting individual treatment response.Frontiers in neurologyArticle
- Acupuncture and related therapies for insomnia symptoms in hypertensive patients: protocol for a network meta-analysis of randomized controlled trials.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the effect of placebo response to acupuncture on subjective and objective sleep indices in patients with chronic insomnia disorder and to understand the effectiveness of acupuncture in the treatment of chronic insomnia disorder (CID). Methods: A comprehensive search was conducted from the inception of the databases to March 17, 2025, encompassing eight databases. A randomized controlled pilot study of collecting acupuncture versus sham acupuncture for the treatment of CID. Systematic collection of acupuncture therapies for CID was performed based on randomized controlled trials (RCTs). Independent researchers critically reviewed the literature, recorded relevant data, and assessed the quality of research. Data were analyzed using RevMan 5.3, Stata 17.0, and TSA 0.9.5.10. Results: The study included a total of 757 patients across 10 trials. Acupuncture demonstrated significant improvement in PSQI scores [MD = -2.60, 95% CI = (-3.24, -1.97), Conclusion: Compared with sham acupuncture, acupuncture is effective in improving subjective sleep quality in patients with CID. However, whether acupuncture improves patients' objective sleep indices compared to sham acupuncture is uncertain and more high-quality clinical trial evidence is needed to validate this. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, Identifier CRD42024541760.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.