Evidence map›Paper›PMID 40371021›Full record

ArticleIndian journal of microbiology2025

Nanotechnology Driven Lipid and Metalloid Based Formulations Targeting Blood-Brain Barrier (3B) for Brain Tumor.

Amulya Jindal, Mainuddin, Anoop Kumar, Ratneshwar Kumar Ratnesh, Jay Singh

Abstract read
In one paragraph

Article in Indian journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  9. Nanoimmunotherapy: the smart trooper for cancer therapy.Exploration of targeted anti-tumor therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amulya JindalDepartment of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh 250005 India.
MainuddinDepartment of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh 250005 India.
Anoop KumarDepartment of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh 250005 India.
Ratneshwar Kumar RatneshDepartment of Electronics and Communication Engineering, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh 250005 India.ORCID 0000-0002-3438-6541
Jay SinghDepartment of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh 221005 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolution of nanotechnology-driven lipid and metalloid-based nanoformulations has garnered significant attention for developing effective drug delivery systems with position/time precision and efficacy. This study focuses on challenges of blood-brain barrier (BBB) and their pivotal role in drug targeting in chronic diseases such as brain tumors (BTs). These formulations encapsulate therapeutic agents within lipidic matrices, enhancing drug solubility, bioavailability, and targeted delivery. The diverse lipid materials used in these nanoformulations highlight their biocompatibility and versatility, covering a wide range of drugs. Emphasis is placed on metal nanoparticles, liposomes, ethosomes, quantum dots, carbon nanotubes, nanorobots, and micelles. The analysis explores their drug loading, stability, release characteristics, and bioavailability modulation. It also delves into the enhanced-permeability and retention (EPR) effect, crucial for passive targeting of tumors. Recent nanocarrier systems enable better penetration of therapeutic compounds through the BBB, addressing treatment failures in invasive BTs.This review highlights the latest nanotechnology developments and potential therapeutic approaches, serving as a valuable resource for researchers, clinicians, and pharmaceutical scientists.

Indexed as

Blood–brain barrierGlioblastomaLipid based drug carrierNanotechnologyTargeted system

Identifiers

PMID40371021
PMCPMC12069182

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.