Evidence map›Paper›PMID 40370993›Full record

ArticleACS pharmacology & translational science2025

Imaging of Microtubules in a Nonhuman Primate Model of Alcohol Use Disorder.

Naresh Damuka, Mack D Miller, Ivan Krizan, Avinash H Bansode, Caleb Bradley, Nagaraju Bashetti, Shanmukha Kumar Jv, Lindsey K Galbo-Thomma, Paul W Czoty, Kiran K Solingapuram Sai

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Imaging microtubule dynamics: A new frontier in biomarker development for neurodegenerative diseases.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Naresh DamukaDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Mack D MillerDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Ivan KrizanDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Avinash H BansodeDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Caleb BradleyDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Nagaraju BashettiDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Vijayawada, Andhra Pradesh 522302, India.
Shanmukha Kumar JvDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Vijayawada, Andhra Pradesh 522302, India.
Lindsey K Galbo-ThommaDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Paul W CzotyDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Kiran K Solingapuram SaiDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID https://orcid.org/0000-0002-6442-5169

Funding

Wake Forest University School of Medicine Alzheimer's Disease Research CenterP30AG072947 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SUZANNE CRAFT · 2021 to 2026
$24.3M
Wake Forest Translational Alcohol Research Center (WF-TARC)P50AA026117 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jeffrey L. Weiner · 2018 to 2026
$16.2M
CTSA UM1 Program at Wake ForestUM1TR004929 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamy D Ard, KRISTIE L FOLEY · 2024 to 2026
$11.9M
MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISMT32AA007565 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRIAN A MCCOOL · 1994 to 2026
$10.1M
NCATS NIH HHS UM1 TR004929NIAAA NIH HHS P50 AA026117NIAAA NIH HHS T32 AA007565NIA NIH HHS P30 AG072947
6 · The paper itself

Abstract

Microtubules (MTs), as structural components of the cytoskeleton, are vital for axonal transport, information processing, and signaling within the brain. Disruption of MT integrity has been associated with neurological disorders, including alcohol use disorder (AUD). This study used positron emission tomography (PET) imaging with the radiotracer [

Identifiers

PMID40370993
PMCPMC12070316

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.