ArticleCureus2025
Infectious Diarrhea in Kidney Transplant Recipients.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Infectious diarrhea represents a significant and frequent complication among kidney transplant recipients, primarily due to the immunosuppressive therapy required to prevent graft rejection. This condition poses substantial risks to both graft function and patient survival, driven by increased susceptibility to opportunistic pathogens and potential medication-related gastrointestinal effects. This study aims to characterize the pathogen spectrum and associated risk factors of infectious diarrhea in a German cohort of kidney transplant recipients, providing insights into regional patterns and clinical implications. Methods A retrospective cohort study was conducted, analyzing 604 patients, including 436 kidney transplant recipients, who were hospitalized with infectious diarrhea (ICD-10 codes A00-A09) at the Universitätsklinikum Düsseldorf (UKD) between January 2019 and December 2023. Nontransplant patients (n = 168) were included as a comparison group to evaluate pathogen distribution and infection risk specific to immunosuppressive therapy in transplant recipients. Pathogen identification was performed focusing on stool samples. Data collected included transplantation status, dates of admission and transplantation, recurrence rates, and detailed immunosuppressive regimens. Statistical analyses were applied to evaluate pathogen distribution, temporal patterns, and the influence of immunosuppression on infection risk. Results The most prevalent pathogens identified among kidney transplant recipients were
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