ArticleCureus2025
Lady in Red: A Fatal Case of Drug Reaction With Eosinophilia and Systemic Symptoms.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, life-threatening drug-induced hypersensitivity reaction. Here, we present the case of a 72-year-old female patient who developed DRESS after starting allopurinol, a well-known causative agent. The patient initially presented to Urgent Care with rash and diarrhea where she was prescribed methylprednisolone dose pack, diphenhydramine as needed, and metronidazole for possible colitis. She had multiple outpatient clinic and emergency department visits for follow-up of fluctuating symptoms and a persistently elevated WBC count despite multiple courses of antibiotics for presumed colitis. After a prolonged clinical course, she was diagnosed with DRESS and admitted for high-dose glucocorticoids. Unfortunately, her condition deteriorated after transfer to the intensive care unit, and she passed away. This case highlights the importance of early consideration, diagnosis, and treatment of DRESS to avoid potentially fatal outcomes.
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