Evidence map›Paper›PMID 40370889›Full record

ArticleCureus2025

Distance Traveled by Colorectal Liver Metastasis Patients to the Nearest Cancer Hospital To Receive Liver Metastasectomy.

Anne Pannekoek, Mengyuan Ruan, Mary Brindle, Quoc-Dien Trinh, George Molina

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anne PannekoekDivision of Surgical Oncology, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Mengyuan RuanCenter for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Mary BrindleAriadne Labs, Brigham and Women's Hospital, Harvard T.H. Chan School of Public Health, Boston, USA.
Quoc-Dien TrinhUrology, University of Pittsburgh Medical Center, Pittsburgh, USA.
George MolinaDivision of Surgical Oncology, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Liver metastasectomy for colorectal liver metastasis (CRLM) has been found to be associated with higher overall survival in select patients. However, this aggressive surgical treatment option is underutilized. At the county level, there is variation in undergoing surgery for CRLM that is associated with county-level poverty rates. However, in contrast, county-level variation in odds of undergoing surgery for stage I colorectal cancer (CRC) was not associated with county-level poverty rates. The objective of this study was to evaluate the impact of distance traveled as a barrier to surgery for CRLM compared to its impact on surgery for stage I CRC. Methods We previously used the Surveillance, Epidemiology, and End Results Research Plus (SEER) database to perform an ecological, cross-sectional, and county-level analysis of the county-level proportion of patients with CRLM diagnosed between January 1, 2010, and December 31, 2018, and as a comparator group, we included county-level proportion of patients with stage I CRC. In this study, we mapped out the variation in receiving surgery for CRLM or for stage I CRC that exists in states that contribute data to SEER. We also evaluated the correlation between the driving distance in miles from the center of a county to the closest National Cancer Institute (NCI) designated cancer center or Commission on Cancer (CoC) accredited cancer program and proportion of patients with CRLM and stage I CRC who received surgery at the county level. Results A total of 191 counties were included, and these included counties in which residing patients had access via land travel to an NCI-designated cancer center or CoC-accredited cancer program. Counties that had high rates of surgery for CRLM had the shortest distance to the nearest NCI-designated cancer center (63.1 and 46.5 miles, respectively). The distance to the nearest NCI-designated cancer center significantly differed between counties that were discordant and favored CRLM surgery and counties that were concordant and low for both CRC and CRLM surgery (p=0.02). The median distance to the nearest NCI-designated cancer center ranged from 46.5 miles to 114.5 miles among these four groups of categorized counties. Including the 25

Indexed as

colorectal liver metastasisdistance from cancer centerliver metastasectomyprimary colorectal cancerunequal access to health care

Identifiers

PMID40370889
PMCPMC12077808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.