Design, synthesis, herbicidal activity, and the molecular docking study of novel phenylpyrazole derivatives with strobilurin moieties.

Wenliang Zhang, Xiaodong Jin, Wenwu Chen, Shulin Hao, Xiaohua Du

Abstract read

In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenliang ZhangCatalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology Hangzhou 310014 Zhejiang China duxiaohua@zjut.edu.cn.ORCID https://orcid.org/0009-0004-7329-174X

Xiaodong JinTaizhou Key Laboratory of Green Agrochemicals Development, Synwill Co., Ltd Taizhou 318000 Zhejiang China.

Wenwu ChenZhejiang Hanghua Technology Co., Ltd Huzhou 313000 China.

Shulin HaoCatalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology Hangzhou 310014 Zhejiang China duxiaohua@zjut.edu.cn.

Xiaohua DuCatalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology Hangzhou 310014 Zhejiang China duxiaohua@zjut.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenylpyrazole derivatives were innovatively designed and synthesized to fabricate novel herbicides containing strobilurin moieties. These resulting compounds were analyzed by nuclear magnetic resonance spectroscopy (NMR) and high-resolution mass spectrometry (HRMS), exhibiting high herbicidal properties against Amaranthus retroflexus. The target compounds were synthesized through cyclization, chlorination, Vilsmeier-Hack reaction, Suzuki coupling reaction, and esterification reactions. The experimental conditions were mild, and the starting materials were easy to obtain, with a separation yield of approximately 80%. Moreover, herbicidal activity of the title compounds was studied

Identifiers

PMID40370840

DOI10.1039/d5ra02377g

PMCPMC12076197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.