ArticleJournal of multidisciplinary healthcare2025
THRIVE Prevent Postoperative Hypoxemia in Elderly Patients Undergoing Laparoscopic Surgery in PACU: A Randomized Controlled Clinical Trial.
Article in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- High-flow nasal cannula for hypoxia in the post-anesthetic recovery unit: A systematic review and meta-analysis.World journal of critical care medicine · 2026Article
- Effect of deep analgosedation vs. intubated general anesthesia on perioperative sedation-related adverse events in older adults undergoing ERCP: protocol for a randomized controlled trial.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Postoperative hypoxemia frequently occurs in elderly individuals undergoing laparoscopic procedures, often leading to severe consequences and prolonged stays in the post-anesthesia care unit (PACU). Conventional oxygen therapy methods are not entirely effective in preventing hypoxemia. Transnasal Humidified Rapid Insufflation Ventilatory Exchange (THRIVE) delivers high-flow oxygen at rates up to 60 L/min, potentially enhancing respiratory function and tolerance to hypoxia. Objective: To assess the effectiveness, safety, and patient tolerance of THRIVE in the early prevention of postoperative hypoxemia in elderly patients following laparoscopic surgery with general anesthesia. Methods: This prospective, multicenter, randomized controlled trial enrolled 200 elderly patients undergoing laparoscopic surgery who were safely extubated after general anesthesia. Participants were randomly allocated to receive either conventional nasal cannula oxygen therapy or THRIVE. Between January 2023 and December 2023, cases were recruited from three participating centers. The main outcome measured was the occurrence of hypoxemia in the PACU. Secondary outcomes encompassed lung ultrasound scores after oxygen therapy, frequency of jaw lifting, reintubation rate, adverse events, and subjective patient comfort. Results: The incidence of hypoxemia was significantly lower in the THRIVE group compared to the standard oxygen therapy group (0% vs 29.2%; χ² = 35.245; Conclusion: THRIVE is an effective strategy for reducing postoperative hypoxemia in elderly individuals undergoing laparoscopic procedures with general anesthesia. It facilitates pulmonary function recovery, enhances patient comfort, and may serve as a valuable intervention in the PACU setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.