Evidence map›Paper›PMID 40370597›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Intensification of 2'-Fucosyllactose biosynthesis pathway by using a novel fucosyltransferase from

Kainuo Zhang, Miaomiao Gao, Chenqi Cao, Mengxin Zhang, Waqar Ahmad, Ahmed Rady, Badr Aldahmash, Tianze Zhu, Shahin Shah Khan, Luo Liu

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In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kainuo Zhang *College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Miaomiao Gao *College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Chenqi CaoCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Mengxin ZhangCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Waqar AhmadCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Ahmed RadyDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Badr AldahmashDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Tianze ZhuBeijing Zeno Biotechnology Development Co. Ltd., Beijing, China.
Shahin Shah KhanCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Luo LiuCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: 2'-Fucosyllactose (2'-FL) is an oligosaccharide that can be synthesized in the human body and is known for its health-promoting and prebiotic effects. The biosynthesis of 2'-FL using microorganisms has received attention recently due to its increased application in nutritional and medical infant formulations. Methods: This work attempts the new application of Results and discussion: The use of constitutive promoters achieved better control over the production of 2'-FL during fed-batch fermentation. After 64 h of fermentation, the modified

Indexed as

2′-fucosyllactosede novo synthesisfermentationFutCBhuman milk oligosaccharide

Identifiers

PMID40370597
PMCPMC12075129

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.