Evidence map›Paper›PMID 40370532›Full record

ReviewActa pharmaceutica Sinica. B2025

Comprehensive investigation of multiple targets in the development of newer drugs for the Alzheimer's disease.

Patil Ashwini, Bodhankar Subhash, Muthal Amol, Dileep Kumar, Pawar Atmaram, Kulkarni Ravindra

Abstract readReview
In one paragraph

Review in Acta pharmaceutica Sinica. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Optimization and Metabolomic Profiling ofInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patil AshwiniDepartment of Pharmaceutical Chemistry, BVDU'S Poona College of Pharmacy, Erandwane Pune-411038, Maharashtra, India.
Bodhankar SubhashDepartment of Pharmacology, BVDU'S Poona College of Pharmacy, Erandwane Pune-411038, Maharashtra, India.
Muthal AmolDepartment of Pharmacology, BVDU'S Poona College of Pharmacy, Erandwane Pune-411038, Maharashtra, India.
Dileep KumarDepartment of Pharmaceutical Chemistry, BVDU'S Poona College of Pharmacy, Erandwane Pune-411038, Maharashtra, India.
Pawar AtmaramDepartment of Pharmaceutics, BVDU'S Poona College of Pharmacy, Erandwane Pune-411038, Maharashtra, India.
Kulkarni RavindraDepartment of Pharmaceutical Chemistry, BVDU'S Poona College of Pharmacy, Erandwane Pune-411038, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease, a significant contributor to dementia, is rapidly becoming a serious healthcare concern in the 21st century. The alarming number of patients with Alzheimer's disease is steadily increasing, which is contributed by the dearth of treatment options. The current treatment for Alzheimer's disease is heavily dependent on symptomatic treatment that has failed to cure the disease despite huge investments in the development of drugs. The clinical treatment of Alzheimer's disease with limited drugs is generally targeted towards the inhibition of

Indexed as

Alzheimer's diseaseAmyloid hypothesisBIN1KinaseNotum inhibitorsTau targeting therapyTrem2

Identifiers

PMID40370532
PMCPMC12069117

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.