Evidence map›Paper›PMID 40370418›Full record

ArticleFood science & nutrition2025

Effects of Biofilm Formation on Gastrointestinal Tolerance, Mucoadhesion and Transcriptomic Responses of Probiotics.

Wang Gao, Huijuan Jing, Bo Qiu, Shuobo Zhang, Jingyi Zhang, Lvwan Xu, Furong Ba, Siyuan Xie, Xiao-Man Liu, Lanjuan Li and 1 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wang GaoJinan Microecological Biomedicine Shandong Laboratory Jinan China.ORCID https://orcid.org/0009-0005-0221-1404
Huijuan JingJinan Microecological Biomedicine Shandong Laboratory Jinan China.
Bo QiuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine Zhejiang University Hangzhou China.
Shuobo ZhangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine Zhejiang University Hangzhou China.
Jingyi ZhangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine Zhejiang University Hangzhou China.
Lvwan XuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine Zhejiang University Hangzhou China.
Furong BaState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine Zhejiang University Hangzhou China.
Siyuan XieState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine Zhejiang University Hangzhou China.
Xiao-Man LiuShandong First Medical University & Shandong Academy of Medical Sciences Jinan China.
Lanjuan LiJinan Microecological Biomedicine Shandong Laboratory Jinan China.ORCID https://orcid.org/0000-0001-6945-0593
Mingfei YaoJinan Microecological Biomedicine Shandong Laboratory Jinan China.ORCID https://orcid.org/0000-0002-4993-3608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic health benefits may be affected by decreased viability during food storage and gastrointestinal transit. Although microencapsulation is an effective protective strategy, its application to probiotics is limited. Currently, research on probiotic biofilms is expanding, with these biofilms being recognized as the fourth generation of probiotics. This study aimed to investigate the effects of biofilm formation on gastrointestinal tolerance and mucoadhesion of three different probiotics:

Indexed as

biofilmgastrointestinal toleranceintestinal adhesionprobiotics

Identifiers

PMID40370418
PMCPMC12076125

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.