ArticleLaryngoscope investigative otolaryngology2025
Sinonasal Sarcoidosis: A Scoping Review of Demographics, Clinical Presentation, and Outcomes.
Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
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Abstract
Objective: Sarcoidosis can involve the head and neck and, in particular, the sinonasal tract. We aim to review the presentation, treatment, and outcomes of sinonasal sarcoidosis. Methods: A PRISMA-ScR-guided scoping review was performed utilizing PubMed, Web of Science, Embase, and SCOPUS to identify case reports describing sarcoidosis in the sinonasal tract. Two reviewers reviewed each article and extracted data. Exclusion criteria consisted of reviews, book chapters, non-English studies, basic science studies, and animal studies. The following data were extracted: patient demographics, symptoms and duration, biopsy status, angiotensinogen converting enzyme level, imaging, treatment, and outcomes. Results: A total of 54 articles (1959-2023) met inclusion criteria, for a total of 103 cases. Median age at diagnosis was 40 years old (18-80 years old). 64% ( Conclusion: Sinonasal sarcoidosis predominantly affects female patients with or without a history of systemic sarcoidosis who present with prolonged nasal obstruction. Most patients have symptomatic improvement with conservative management; however, a select subset of patients may respond well to surgical management. Further investigation into the workup, indications for surgical intervention, and treatment algorithm is warranted to reduce disease morbidity. Level of Evidence: NA.
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