Evidence map›Paper›PMID 40370311›Full record

SynthesisAmerican journal of men's health

Health-Related Quality of Life Following Treatment for Testicular Cancer: A Qualitative Systematic Review.

Louis Fox, Charlotte Moss, Tobias Gregor Hauser, Isolt Reardon, Netty Kinsella, Walter Cazzaniga, Mieke Van Hemelrijck, David Nicol

Abstract readSystematic Review
In one paragraph

Synthesis in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Louis FoxCentre for Cancer, Society, and Public Health, King's College London, UK.ORCID 0000-0002-8280-1797
Charlotte MossCentre for Cancer, Society, and Public Health, King's College London, UK.
Tobias Gregor HauserDepartment of Urology, Barmherzige Brueder Hospital Munich, Germany.ORCID 0000-0001-7097-2815
Isolt ReardonCentre for Cancer, Society, and Public Health, King's College London, UK.
Netty KinsellaUrology Unit, The Royal Marsden NHS Foundation Trust, London, UK.
Walter CazzanigaUrology Unit, The Royal Marsden NHS Foundation Trust, London, UK.
Mieke Van HemelrijckCentre for Cancer, Society, and Public Health, King's College London, UK.
David NicolUrology Unit, The Royal Marsden NHS Foundation Trust, London, UK.ORCID 0000-0003-0107-6990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testicular cancer (TCa) can precipitate ongoing psychosocial/physical morbidity post-treatment, despite high rates of cure. We conducted a systematic review to synthesise three decades of primary qualitative research on health-related quality of life (HRQoL) to inform the design of supportive care pathways. We queried MEDLINE/PubMed, PsycINFO, CINAHL, and Web of Science for all qualitative studies published up to 26 October 2022 examining issues relevant to HRQoL in post-treatment TCa patients. Two independent reviewers appraised included studies for methodological quality using established guidance for evidence-based public health policy and analysed findings via thematic synthesis. Studies were analytically weighted by study quality. Studies were evaluated using GRADE-CERQual to produce confidence levels in findings. We included 18 studies, comprising 387 participants. Seven studies were graded high quality, eight medium quality, and three low quality. Emergent analytical themes were: (a) Residual psychological injury; (b) Information deficits and unnecessary anxiety; (c) Thwarted life trajectory; (d) Social disruption; (e) Undermined youth; (f) Health service abandonment; (g) Long-term sexual problems; and (h) Maladaptive coping and post-traumatic stress. All findings were deemed 'high confidence', except theme (g), which was of 'moderate confidence'. A limitation of the review was the relative dominance of Anglophone countries in the included studies. Some men treated for TCa are at risk of a range of post-treatment HRQoL issues, particularly psychosocial issues. Some individuals may be more at risk than others, based on specific personality traits, access to accurate and complete information about treatment recovery, and individual coping responses.

Indexed as

Quality of LifeTesticular NeoplasmsAdaptation, PsychologicalHumansMaleQualitative Researchbody imagehealth-related quality of lifequalitative researchsocial supporttesticular cancer

Identifiers

PMID40370311
PMCPMC12081962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.