ArticleFuture medicinal chemistry2025
Synthesis, antimicrobial evaluation, HPLC-based compound accumulation and docking studies of 2-methoxybenzoyl thioureas.
Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn this study, we presented the synthesis, antimicrobial activity, High Performance Liquid Chromatography (HPLC)-based compound accumulation and molecular docking of 2-methoxybenzoyl substituted thiourea derivatives. MATERIALS AND
methodsThe antimicrobial activity of a total of eight synthesized compounds was evaluated against seven species of bacteria and fungi. HPLC-based compound accumulation assay, molecular docking, in silico toxicity and ADME analyses were performed for selected compounds for further evaluation of compound activity relationship. RESULTS AND DISCUSSION: The compounds exhibited greater activity against fungi than bacteria, with compounds
conclusionThe results suggest that optimizing the position of substituents on the phenyl rings of acyl thioureas could enhance the antimicrobial activity of our compounds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.