Evidence map›Paper›PMID 40370095›Full record

ReviewHistology and histopathology2026

Trophoblast-derived proteins and their effects on the pathogenesis of preeclampsia.

Ju Yang, Yanan Wang, Xueling Chen, Haifeng Zhang, Yunshan Xue, Haibin Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histology and histopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ju YangDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.
Yanan WangDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.
Xueling ChenDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.
Haifeng ZhangDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.
Yunshan XueDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China.
Haibin ChenDepartment of Histology and Embryology, Shantou University Medical College, Shantou, China. chenhb@stu.edu.cn.

Funding

Department of Education of Guangdong Province 2020KTSCX036Department of Education of Guangdong Province 2024ZDZX2027Health Commission of Guangdong Province A2023342Natural Science Foundation of Guangdong Province 2021A1515011205Natural Science Foundation of Guangdong Province 2023A1515010544
6 · The paper itself

Abstract

Trophoblast cells are crucial structural units of the placenta, responsible for maintaining its integrity and function. These cells synthesize and secrete specific proteins that play essential roles in placental vascularization, maternal and fetal immune tolerance, and other critical processes. An abnormal level of trophoblast-derived secreted proteins has been closely linked to pregnancy-related diseases. Preeclampsia, a severe complication of pregnancy characterized by

Indexed as

Pre-EclampsiaTrophoblastsAnimalsFemaleHumansPlacentaPregnancy

Identifiers

PMID40370095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.