Evidence map›Paper›PMID 40370090›Full record

ReviewACS applied materials & interfaces2025

Design and Applications of Polymersomes for Oral Drug Administration.

Wing-Fu Lai

Abstract readReview
In one paragraph

Review in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Amine-Functionalized NiCoFeInternational journal of nanomedicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Wing-Fu LaiSchool of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, United Kingdom.ORCID 0000-0003-0585-6396

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymersomes are nanostructures consisting of a hollow aqueous compartment enclosed by a coating of amphiphilic block copolymers. Owing to the entangled nature of their membrane, polymersomes exhibit higher mechanical stability than some other extensively studied nanostructures such as liposomes. This also enables the properties of the polymersome membrane to be more easily tuned to meet practical needs, making polymersomes promising carriers for drug delivery. Since the turn of the last century, the use of polymersomes has been exploited in diverse areas, ranging from protein therapy to medical imaging. Yet, discussions exploring the opportunities and challenges of the development of polymersomes for oral drug administration have been scant. This review addresses this gap by offering a snapshot of the current advances in the design, fabrication, and use of polymersomes as oral drug carriers. It is hoped that this review will not only highlight the practical potential of polymersomes for oral drug administration but will also shed light on the challenges determining the wider clinical potential of polymersomes in the forthcoming decades.

Indexed as

Drug CarriersDrug Delivery SystemsNanostructuresPolymersAdministration, OralAnimalsHumansDrug CarriersPolymersamphiphilicityblock copolymerscolloidal behaviorcontrolled releasedrug deliveryoral administrationpolymersomes

Identifiers

PMID40370090
PMCPMC12123574

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.