Evidence map›Paper›PMID 40369559›Full record

ArticleChild and adolescent psychiatry and mental health2025

Bidirectional relationships between intolerance of uncertainty and generalized anxiety among adolescents: insights from cross-lagged panel network analysis.

Haoxian Ye, Yunyi Li, Yike Huang, Yiming Zhang, Jiaxiong Zhang, Jiaqi Wang, Keying Liu, Yuyi Yao, Xinyu Shi, Yijia Liu and 1 more

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In one paragraph

Article in Child and adolescent psychiatry and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Why climate action is an opportunity multiplier for mental health.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haoxian YeSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Yunyi LiSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Yike HuangSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Yiming ZhangSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Jiaxiong ZhangSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Jiaqi WangSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Keying LiuSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Yuyi YaoSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Xinyu ShiSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Yijia LiuSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China.
Fang FanSchool of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangdong Emergency Response Technology Research Center for Psychological Assistance in Emergencies, South China Normal University, Guangzhou, China. fangfan@scnu.edu.cn.

Funding

National Natural Science Foundation of China 32271135
6 · The paper itself

Abstract

backgroundIntolerance of uncertainty (IU) has received increasing attention for its role in the development and maintenance of generalized anxiety. However, little is known about the temporal and causal relationships between IU and generalized anxiety, particularly in adolescents. Furthermore, much of the existing literature treats IU and generalized anxiety as unidimensional constructs, limiting a detailed understanding of their internal elements and specific symptom interactions. To address the gaps, this study employed a cross-lagged panel network (CLPN) approach to examine the temporal interactions and predictive relationships between IU elements and generalized anxiety symptoms.

methodsA sample of 7,434 nonclinical adolescents (mean

resultsBidirectional predictive relationships were found between IU elements and generalized anxiety symptoms, with generalized anxiety symptoms more frequently predicting IU elements. The generalized anxiety symptom named "nervousness" was the strongest predictor of increases in both IU elements and other generalized anxiety symptoms over time, while the IU elements named "frustration" and "work with hindrance" were the strongest predictors of future generalized anxiety symptoms.

conclusionsThis study provides new insights into the reciprocal relationships between IU and generalized anxiety among adolescents, highlighting the complex interplay between vulnerability and mental health problems. By identifying key IU elements and generalized anxiety symptoms that drive these relationships, the findings contribute to a more nuanced understanding of adolescent psychopathology and inform targeted interventions.

Indexed as

AdolescentsBidirectionalCross-lagged panel networkGeneralized anxietyIntolerance of uncertainty

Identifiers

PMID40369559
PMCPMC12079871

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