Evidence map›Paper›PMID 40369543›Full record

ArticleJournal of nanobiotechnology2025

A novel tri-mode detection platform for ampicillin and drug resistance genes by CRISPR-driven luminescent nanozymes.

Tao Zhang, Guiling Liu, Siwei Sun, Zongwu Meng, Yuzhe Qiu, Ping Ding

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tao ZhangXiangya School of Public Health, Central South University, Changsha, Hunan, 410078, China.
Guiling LiuXiangya School of Public Health, Central South University, Changsha, Hunan, 410078, China.
Siwei SunSchool of Stomatology, Fudan University, Shanghai, 200030, China.
Zongwu MengXiangya School of Public Health, Central South University, Changsha, Hunan, 410078, China.
Yuzhe QiuXiangya School of Public Health, Central South University, Changsha, Hunan, 410078, China.
Ping DingXiangya School of Public Health, Central South University, Changsha, Hunan, 410078, China. Pingshui@csu.edu.cn.

Funding

the National Natural Science Foundation of China 82373635
6 · The paper itself

Abstract

The antibiotic residues pose significant risks for bacterial resistance. To address the practical requirements for rapid, accurate, and on-site detection of antibiotic residues and monitoring the abundance of associated resistance genes, we report a smartphone-integrated multi-mode platform. The platform is aimed to simultaneous, accurate, and visual quantitative detection of ampicillin (AMP) and β-lactam antibiotic resistance genes (blaTEM). Specifically, we developed a magnetically controlled fluorescence, colorimetric, and photothermal biosensor based on a magnetic separation unit (aminated modified complementary DNA chain (NH

Indexed as

AmpicillinAnti-Bacterial AgentsBiosensing TechniquesCRISPR-Cas SystemsDrug Resistance, BacterialAptamers, Nucleotidebeta-LactamasesClustered Regularly Interspaced Short Palindromic RepeatsColorimetryFerrosoferric OxideIndolesLimit of DetectionManganese CompoundsOxidesPolymersSmartphoneAmpicillinAnti-Bacterial AgentsAptamers, Nucleotidebeta-LactamasesFerrosoferric OxideIndolesManganese Compoundsmanganese dioxideOxidespolydopaminePolymersAmpicillinAptamerBlaTEMCRISPR/Cas12aTri-mode detectionVisual detection

Identifiers

PMID40369543
PMCPMC12076998

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.