Evidence map›Paper›PMID 40369383›Full record

ArticleWorld journal of microbiology & biotechnology2025

Overexpression of the Wbl family regulator whiD

Xuedong Zhang, Jiabin Wang, Haoran Shi, Na Zhou, Shanshan Li, Lan Ye, Wensheng Xiang, Xiangjing Wang, Yanyan Zhang

Abstract read
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In one paragraph

Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuedong Zhang *Key Laboratory of Agricultural Microbiology of Heilongjiang Province, Northeast Agricultural University, Harbin, 150030, China.
Jiabin Wang *Key Laboratory of Agricultural Microbiology of Heilongjiang Province, Northeast Agricultural University, Harbin, 150030, China.
Haoran ShiKey Laboratory of Agricultural Microbiology of Heilongjiang Province, Northeast Agricultural University, Harbin, 150030, China.
Na ZhouState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Shanshan LiState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Lan YeKey Laboratory of Agricultural Microbiology of Heilongjiang Province, Northeast Agricultural University, Harbin, 150030, China.
Wensheng XiangKey Laboratory of Agricultural Microbiology of Heilongjiang Province, Northeast Agricultural University, Harbin, 150030, China.
Xiangjing WangKey Laboratory of Agricultural Microbiology of Heilongjiang Province, Northeast Agricultural University, Harbin, 150030, China. wangneau2013@163.com.
Yanyan ZhangState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. yyzhang@ippcaas.cn.

Funding

National Natural Science Foundation of China 32272635the Agricultural Science and Technology Innovation Program CAAS-CSCB-202401
6 · The paper itself

Abstract

Streptomyces species are prolific producers of a diverse array of bioactive secondary metabolites (SMs), which constitute approximately two-thirds of natural product-based pharmaceuticals with significant clinical, agricultural, and biotechnological applications. However, the regulatory mechanisms underlying the biosynthesis of these compounds remain poorly understood, impeding the development of high-yielding strains for industrial production. Herein, we investigated the role of the WhiB-like (Wbl) family transcriptional regulator, WhiD

Indexed as

Bacterial ProteinsSecondary MetabolismStreptomycesTranscription FactorsAnthraquinonesBenzoisochromanequinonesBiosynthetic PathwaysGene Expression ProfilingGene Expression Regulation, BacterialIvermectinMacrolidesMultigene FamilyactinorhodinAnthraquinonesavermectinBacterial ProteinsBenzoisochromanequinonesIvermectinMacrolidesTranscription FactorsActK/R-KelR regulatory cascadeHigh-yielding strategiesSecondary metabolitesStreptomyces bingchenggensisWhiDsbh

Identifiers

PMID40369383

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.