Evidence map›Paper›PMID 40369376›Full record

ArticleSurgery today2025

Clinical outcomes of initial inside stenting for preoperative malignant hilar biliary obstruction in patients with jaundice.

Ryo Sugiura, Masaki Kuwatani, Kazumichi Kawakubo, Hiroki Yonemura, Shunichiro Nozawa, Shoya Shiratori, Soichiro Oda, Kimitaka Tanaka, Satoshi Hirano, Naoya Sakamoto

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ryo SugiuraDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
Masaki KuwataniDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan. mkuwatan@med.hokudai.ac.jp.
Kazumichi KawakuboDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
Hiroki YonemuraDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
Shunichiro NozawaDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
Shoya ShiratoriDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
Soichiro OdaDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
Kimitaka TanakaDepartment of Gastroenterological Surgery II, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Satoshi HiranoDepartment of Gastroenterological Surgery II, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Naoya SakamotoDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEndoscopic nasobiliary drainage (ENBD) is a widely used primary approach for preoperative endoscopic biliary drainage (PEBD) for malignant hilar biliary obstruction (MHBO) although the utility of inside stenting (IS) remains unknown. This study aimed to compare the clinical outcomes of IS and ENBD as the initial PEBD.

methodsThis retrospective, single-center study included patients with MHBO who underwent IS or ENBD as the initial PEBD and before laparotomy for radical surgical resection at the study institution. The primary outcome was the clinical success rate of the initial PEBD method.

resultsThe study included 28 and 38 patients who underwent IS and ENBD, respectively, for initial PEBD. The clinical success rates in patients who underwent IS and ENBD were 78.6% and 97.4%, respectively (P = 0.04). Clinical failure was more frequent in patients with jaundice undergoing IS (42.9%) than in those without jaundice undergoing IS and those with or without jaundice undergoing ENBD (0-4.2%; P < 0.01). The rates of cholangitis and PEBD-related adverse events, the cumulative incidence of PEBD dysfunction, and postoperative survival in patients undergoing IS and ENBD did not differ to a statistically significant extent.

conclusionsClinical failure of initial PEBD was more frequent in patients with jaundice undergoing IS than in those undergoing ENBD during the initial preoperative period of workup and drainage period.

Indexed as

Bile Duct NeoplasmsCholestasisDrainageJaundiceJaundice, ObstructivePreoperative CareStentsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSurvival RateClinical successEndoscopic biliary stentingEndoscopic nasobiliary drainageInside stentingPreoperative biliary drainage

Identifiers

PMID40369376

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.