ArticleDiscover oncology2025
Photodynamic therapy in esophageal cancer: trends, innovations, and future directions from a global perspective (1985-2024).
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- [Hollow copper sulfide nanocomposites combined with photothermal and photodynamic therapy inhibits malignant behaviors of esophageal cancer cells].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEsophageal cancer (EC) is a leading cause of cancer-related deaths worldwide. Photodynamic therapy (PDT) has emerged as a promising, minimally invasive treatment for EC due to its high selectivity. However, a comprehensive bibliometric analysis of PDT in EC is lacking. This study aims to assess research trends, key contributors, and emerging themes in PDT for EC from 1985 to 2024.
methodsWe performed a bibliometric analysis using data from the Web of Science Core Collection. VOSviewer, CiteSpace, and the R package 'bibliometrix' were employed to examine publication trends, collaboration networks, and primary research themes related to PDT in EC.
resultsThe analysis included 581 publications by 2037 researchers from 593 institutions across 40 countries. The United States, China, and England were the top contributors, with significant input from the Mayo Clinic and Thompson Cancer Survival Center. Photodiagnosis and Photodynamic Therapy was the most prolific journal, while Gastrointestinal Endoscopy received the highest citations. Research areas covered various aspects of PDT in EC, including its combination with endoscopic treatments, use of photosensitizers, palliative care applications, biological mechanisms, and nanoparticle drug delivery advancements. Emerging themes highlighted the application of nanotechnology in drug delivery, integration of immunotherapy, and exploration of the tumor microenvironment.
conclusionThis bibliometric study reveals a global expansion in PDT research for EC, emphasizing new directions such as nanotechnology-enhanced drug delivery, immunotherapy integration, and tumor microenvironment studies. These advancements are expected to improve PDT's effectiveness, particularly in overcoming the limitations of current treatments for deeper and more advanced EC cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.